| 罗 婷,达 婷,何 蕊,卞锦花,薛芳芳.宫颈癌患者四维能量多普勒超声血管血流参数与疾病分期的相关性分析[J].,2024,(2):309-313 |
| 宫颈癌患者四维能量多普勒超声血管血流参数与疾病分期的相关性分析 |
| Correlation between Blood Flow Parameters of Four-dimensional Power Doppler Ultrasound and Disease Stage in Patients with Cervical Cancer |
| 投稿时间：2023-03-10 修订日期：2023-03-31 |
| DOI：10.13241/j.cnki.pmb.2024.02.020 |
| 中文关键词: 宫颈癌 四维能量多普勒超声 血管血流参数 疾病分期 |
| 英文关键词: Cervical cancer Four-dimensional power Doppler ultrasound Blood flow parameters of blood vessels Disease stage |
| 基金项目:陕西省自然科学基础研究计划项目（S2020-JC-QN-1840） |
|
| 摘要点击次数: 419 |
| 全文下载次数: 293 |
| 中文摘要: |
| 摘要 目的：探究宫颈癌患者四维能量多普勒超声血管血流参数与其疾病分期的相关性。方法：选择2019年8月至2022年7月于我院接受治疗的80例确诊为宫颈癌患者为研究组，另取同期入院检测的50例宫颈癌上皮内瘤变患者为CIN组，取同期确诊为子宫良性病变的50例患者为对照组，分别对其进行了四维能量多普勒超声检测，对比三组患者超声参数差异，将研究组患者按照FIGO标准区分为不同疾病分期（I期23，II期34，III期23），对比不同分期宫颈癌患者超声参数差异，通过绘制受试者曲线（ROC）的方式评估超声参数对不同宫颈癌分期的鉴别价值。结果：研究组、CIN组和对照组之间超声血流参数PSV及RI存在显著差异，同时两两相比较同样组间差异具有统计学意义（P<0.05）；不同宫颈癌分期患者超声血流参数之间存在显著差异，以FIGO III期的PSV最高，RI最低，各组两两相比较同样差异具有统计学意义（P<0.05）；PSV对FIGO I期至FIGO II期诊断AUC为0.6829（95% CI=0.5333-0.8324，P=0.0200），对FIGO II期至FIGO III期诊断AUC为0.7698（95% CI=0.6402-0.8995，P=0.0006），对FIGO I期至FIGO III期诊断AUC为0.7505（95% CI=0.6072-0.8937，P=0.0036）；RI对FIGO I期至FIGO II期诊断AUC为0.9309（95% CI=0.8662-0.9957，P<0.0001），对FIGO II期至FIGO III期诊断AUC为0.7148（95% CI=0.5804-0.8493，P=0.0063），对FIGO I期至FIGO III期诊断AUC为0.9811（95% CI=0.9504-1.000，P<0.0001）。结论：宫颈癌患者四维能量多普勒超声血管血流参数与其疾病分期具有一定的关联，将PSV和RI指数应用于宫颈癌分期鉴别中具有较好的应用价值，具有推广应用意义。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the correlation between the blood flow parameters of four-dimensional power Doppler ultrasound and the disease stage in patients with cervical cancer. Methods: 80 patients with cervical cancer who were treated in our hospital from August 2019 to July 2022 were selected as the study group, another 50 patients with cervical intraepithelial neoplasia who were admitted to the hospital during the same period were selected as the CIN group, and 50 patients with benign lesions of the uterus at the same period were selected as the control group. Four-dimensional power Doppler ultrasound was performed on them respectively to compare the differences of ultrasound parameters between the three groups, The patients in the study group were divided into different disease stages (stage I 23, stage II 34, stage III 23) according to the FIGO standard, and the differences of ultrasound parameters in different stages of cervical cancer were compared, and the differential value of ultrasound parameters in different stages of cervical cancer was evaluated by drawing the subject curve (ROC). Results: There were significant differences in ultrasound blood flow parameters PSV and RI between the study group, CIN group and the control group, and the difference between the two groups was statistically significant (P<0.05); There were significant differences in ultrasound blood flow parameters among patients with different stages of cervical cancer. PSV of FIGO III was the highest and RI was the lowest. The same difference was statistically significant between the two groups (P<0.05); The AUC of PSV was 0.6829 (95% CI=0.5333-0.8324, P=0.0200) for FIGO I to FIGO II, 0.7698 (95% CI=0.6402-0.8995, P=0.0006) for FIGO II to FIGO III, and 0.7505 (95% CI=0.6072-0.8937, P=0.0036) for FIGO I to FIGO III; The AUC of RI was 0.9309 (95% CI=0.8662-0.9957, P<0.001) for FIGO I to FIGO II, 0.7148 (95% CI=0.5804-0.8493, P=0.0063) for FIGO II to FIGO III, and 0.9811 (95% CI=0.9504-1.000, P<0.001) for FIGO I to FIGO III. Conclusion: The blood flow parameters of four-dimensional power Doppler ultrasound in patients with cervical cancer have a certain correlation with their disease stages. The application of PSV and RI index in the differentiation of cervical cancer stages has good application value and has the significance of popularization and application. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
