| 常子维,唐海龙,张 娟,许东亮,李秋红.儿童呼吸道合胞病毒感染情况研究[J].,2023,(24):4664-4668 |
| 儿童呼吸道合胞病毒感染情况研究 |
| Study on the Infection of Parainfluenza Virus and Mycoplasma Pneumoniae in Children |
| 投稿时间：2023-06-30 修订日期：2023-07-23 |
| DOI：10.13241/j.cnki.pmb.2023.24.012 |
| 中文关键词: 呼吸道合胞病毒 细支气管炎 呼吸道感染 哮喘 |
| 英文关键词: Respiratory syncytial virus Bronchiolitis Respiratory tract infection Asthma |
| 基金项目:国家自然科学基金项目（82100218） |
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| 摘要点击次数: 507 |
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| 中文摘要: |
| 摘要 目的：检测2011-2021年期间住院患儿血清中的呼吸道合胞病毒抗体IgM，分析并探讨呼吸道合胞病毒的流行病学特征。方法：应用酶联免疫分析方法定性检测患儿血清中的呼吸道合胞病毒抗体IgM，采用卡方检验对不同年份、性别、年龄及季节的感染率进行分析。结果：呼吸道合胞病毒总感染率为4.3%，每年女性患儿比男性患儿感染率高，性别之间无明显统计学差异（P>0.05）。在不同年龄段上，从2011-2014年及2020年，RSV感染率主要集中在0-8岁之间，随着年龄增长，住院患儿几乎没有感染RSV。从2015-2019年，0-13岁基本上每个年龄里都有RSV的感染；在2021年，RSV感染率主要是1-3岁。在每年的四季中，呼吸道合胞病毒感染率各不相同，一般在冬季感染率较高，依次是春季、秋季和夏季，各个季节之间无明显统计学差异（P>0.05）。结论：呼吸道合胞病毒感染可引起儿童毛细支气管炎，是引起儿童哮喘的重要原因，并且可加重哮喘的症状，掌握儿童呼吸道合胞病毒流行病学特征，有助于了解儿童感染特点，有利于儿童疾病的诊断与治疗。 |
| 英文摘要: |
| ABSTRACT Objective: To detect the respiratory syncytial virus antibody IgM in the serum of hospitalized children from 2011-2021, and analyze and explore the epidemiological characteristics of respiratory syncytial virus. Methods: Enzyme linked immunosorbent assay(ELISA) was used to qualitatively detect the respiratory syncytial virus antibody IgM in the serum of children. Chi-square test was used to analyze the infection rates in different years, genders, ages, and seasons. Results: The total infection rate of respiratory syncytial virus was 4.3%, and the infection rate of female children was higher than that of male children every year. There was no significant statistical difference between genders(P>0.05). At different age groups, from 2011 to 2014 and 2020, the RSV infection rate was mainly concentrated between 0 and 8 years old. As age increased, hospitalized children had almost no RSV infection. From 2015 to 2019, almost every age group aged 0-13 had RSV infection; In 2021, the RSV infection rate was mainly between 1-3 years old. In the four seasons of each year, the infection rate of respiratory syncytial virus varies. Generally, the infection rate is higher in winter, followed by spring, autumn, and summer, with no significant statistical difference between each season （P>0.05）. Conclusion: Respiratory syncytial virus infection can cause bronchiolitis in children, which is an important cause of asthma and can exacerbate the symptoms of asthma. Mastering the epidemiological characteristics of respiratory syncytial virus in children can help understand the characteristics of infection in children, and is beneficial for the diagnosis and treatment of childhood diseases. |
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