| 王 欢,王 辉,卜 岗,王崇祥,赵 博,聂会勇.原发性三叉神经痛和疱疹后三叉神经痛临床特征及射频热凝术后效果分析[J].,2023,(22):4348-4353 |
| 原发性三叉神经痛和疱疹后三叉神经痛临床特征及射频热凝术后效果分析 |
| Clinical Characteristics and Postoperative Effects of Radiofrequency Thermocoagulation for Primary Trigeminal Neuralgia and Postherpetic Trigeminal Neuralgia |
| 投稿时间：2023-06-06 修订日期：2023-06-30 |
| DOI：10.13241/j.cnki.pmb.2023.22.030 |
| 中文关键词: 三叉神经痛 射频热凝术 临床疗效 疼痛 |
| 英文关键词: Trigeminal neuralgia Radiofrequency thermocoagulation Clinical efficacy Pain |
| 基金项目:陕西省重点研发计划项目（2020SF-131） |
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| 中文摘要: |
| 摘要 目的：探讨原发性三叉神经痛（PTN）和疱疹后三叉神经痛（PHN）的临床特征，并比较经卵圆孔射频热凝术（RF-TC）治疗PTN和PHN的临床疗效。方法：随机选取2019年1月至2020年8月在我院治疗的三叉神经痛患者123例，其中原发性三叉神经痛90例，带状疱疹后神经痛33例。所有患者均通过RF-TC进行治疗，治疗后通过视觉模拟量表（VAS）、巴罗神经研究所疼痛强度量表对面部疼痛评分进行疼痛评估，通过巴罗神经研究所麻木评分进行麻木评定，通过健康问卷-9对患者抑郁情况进行评估，通过匹斯堡睡眠质量指数测量患者心理状态。结果：PTN患者发病年龄显著低于PHN患者（P<0.05），而病程显著高于PHN患者（P<0.05）；PHN患者的眼支发生率高于PTN患者（39.39% vs 8.89%, P<0.05）。两组患者经RF-TC治疗前后VAS评分无显著差异（P>0.05）。PHN组从轻度到重度影响睡眠质量的比例显著高于PTN组（30.30% vs 10.00%, P<0.05）。PTN组患者治疗后中重度抑郁患者比例显著高于PHN组患者（21.11% vs 9.09%, P<0.05）。两组患者经RF-TC治疗后，临床治疗有效率、面麻木程度以及巴罗神经研究所疼痛强度量表评定的面部疼痛无显著差异（P>0.05）。结论：经卵圆孔射频热凝术治疗原发性三叉神经痛和带状疱疹后三叉神经痛是安全有效的，但治疗后疱疹后三叉神经痛失眠的发生率较高，而原发性三叉神经痛的抑郁发生率较高。 |
| 英文摘要: |
| ABSTRACT Objective: T Exploring the clinical characteristics of primary trigeminal neuralgia (PTN) and postherpetic trigeminal neuralgia (PHN), and studying the clinical efficacy of radiofrequency thermocoagulation through foramen ovale (RF-TC) in the treatment of PTN and PHN. Methods: Randomly select 123 patients with trigeminal neuralgia who were treated in our hospital from January 2019 to August 2020, including 90 cases of primary trigeminal neuralgia and 33 cases of postherpetic neuralgia. All patients were treated with RF-TC. After treatment, pain was assessed using the Visual Analog Scale (VAS), Barrow Neurological Institute Pain Intensity Scale, and Facial Pain Score. numbness was assessed using the Barrow Neurological Institute numbness score. Depression was assessed using the Health Questionnaire-9. The psychological state of patients was measured using the Pittsburgh Sleep Quality Index. Results: The onset age of PTN patients was significantly lower than that of PHN patients(P<0.05), and the course of disease was significantly higher than that of PHN patients(P<0.05), while the incidence of ocular branches in PHN patients was higher than that in PTN patients (39.39% vs 8.89%, P<0.05). There was no significant difference in VAS scores between the two groups of patients before and after RF-TC treatment (P>0.05). The proportion of mild to severe effects on sleep quality in the PHN group was significantly higher than that in the PTN group (51.51% vs 35.56%, P<0.05). The proportion of patients with moderate to severe depression in the PTN group after treatment was significantly higher than that in the PHN group (21.11% vs 9.09%, P<0.05). After RF-TC treatment, there was no significant difference in clinical treatment efficacy, facial numbness, and facial pain assessed by the Barrow Neurology Institute Pain Intensity Scale between the two groups of patients(P>0.05). Conclusion: Radiofrequency thermocoagulation through the foramen ovale is a safe and effective treatment for primary trigeminal neuralgia and post herpetic trigeminal neuralgia. However, the incidence of insomnia in post herpetic trigeminal neuralgia is higher, while the incidence of depression in primary trigeminal neuralgia is higher. |
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