| 宛久会,马士辉,胡 玲,石玮玮,吴梦娇,易 松.穴位贴敷联合阶段性康复功能训练对股骨颈骨折术后患者功能康复、血清疼痛因子和骨代谢标志物的影响[J].,2023,(1):177-181 |
| 穴位贴敷联合阶段性康复功能训练对股骨颈骨折术后患者功能康复、血清疼痛因子和骨代谢标志物的影响 |
| Effects of Acupoint Application Combined with Staged Rehabilitation Function Training on Functional Rehabilitation, Serum Pain Factors and Bone Metabolism Markers in Patients with Femoral Neck Fracture after Operation |
| 投稿时间：2022-03-30 修订日期：2022-04-27 |
| DOI：10.13241/j.cnki.pmb.2023.01.035 |
| 中文关键词: 穴位贴敷 阶段性康复功能训练 股骨颈骨折 功能康复 疼痛因子 骨代谢标志物 |
| 英文关键词: Acupoint application Staged rehabilitation function training Femoral neck fracture Functional rehabilitation Pain factors Bone metabolic markers |
| 基金项目:四川省干部保健委员会科研项目（2019-606） |
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| 中文摘要: |
| 摘要 目的：探讨穴位贴敷联合阶段性康复功能训练对股骨颈骨折术后患者功能康复、血清疼痛因子和骨代谢标志物的影响。方法：纳入四川省骨科医院2021年1月~2021年10月期间收治的股骨颈骨折患者150例。根据信封抽签法将患者分为对照组（75例）和观察组（75例），对照组接受阶段性康复功能训练，观察组接受穴位贴敷联合阶段性康复功能训练，两组均干预3个月。3个月后，观察两组功能康复、视觉疼痛模拟评分法（VAS）评分、血清疼痛因子和骨代谢标志物情况，记录两组术后并发症发生率。结果：两组干预3个月后Barthel指数和Harris髋关节评分均较干预前升高，且观察组高于对照组（P<0.05）。两组干预1个月后、干预2个月后、干预3个月后视觉疼痛模拟评分法（VAS）评分逐渐下降，且观察组低于对照组（P<0.05）。两组干预3个月后骨特异性碱性磷酸酶（BALP）、骨保护素（OPG）升高，且观察组高于对照组；抗酒石酸盐酸性磷酸酶异构体（TRACP-5b）、Ⅰ型胶原羧基端肽β特殊序列（βCTX）水平降低，且观察组低于对照组（P<0.05）。两组干预3个月后缓激肽（BK）、前列腺素E2（PGE2）、5-羟色胺（5-HT）、脑内神经肽Y（NPY）水平降低，且观察组低于对照组（P<0.05）。两组术后并发症发生率组间对比无统计学差异（P>0.05）。结论：穴位贴敷联合阶段性康复功能训练可促进对股骨颈骨折患者术后功能恢复，减轻术后疼痛，可能与调节骨代谢相关标志物水平有关。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effects of acupoint application combined with staged rehabilitation function training on functional rehabilitation, serum pain factors and bone metabolism markers in patients with femoral neck fracture after operation. Methods: 150 patients with femoral neck fracture who were treated in Sichuan Orthopedic Hospital from January 2021 to October 2021 were included. According to the envelope lottery method, the patients were divided into control group (75 cases) and observation group (75 cases). The control group received staged rehabilitation function training, and the observation group received acupoint application combined with staged rehabilitation function training. Both groups were intervened for 3 months. After 3 months, the functional rehabilitation, visual pain analogue scale (VAS) score, serum pain factors and bone metabolism markers in the two groups were observed, and the incidence of postoperative complications in the two groups was recorded. Results: 3 months after intervention, Barthel Index and Harris hip score in the two groups were higher than those before treatment, and the observation group was higher than that in the control group (P<0.05). 1 month after intervention, 2 months after intervention and 3 months after intervention, the scores of visual pain analogue scale (VAS) in the two groups decreased gradually, and the scores in the observation group were lower than those in the control group (P<0.05). 3 months after intervention, bone specific alkaline phosphatase (BALP) and osteoprotegerin (OPG) increased in the two groups, and the observation group was higher than the control group. The levels of tartrate resistant hydrochloric acid phosphatase isomer (TRACP-5b), type I collagen carboxyl terminal peptide β Special sequence (β-CTX) were decreased, and the observation group was lower than the control group (P<0.05). 3 months after intervention, the levels of bradykinin (BK), prostaglandin E2 (PGE2), 5-hydroxytryptamine (5-HT) and neuropeptide Y (NPY) in two groups were decreased, and the observation group was lower than the control group (P<0.05). There was no significant difference in the incidence of postoperative complications between the two groups (P>0.05). Conclusion: Acupoint application combined with staged rehabilitation function training can promote the postoperative functional recovery of patients with femoral neck fracture and reduce postoperative pain, which may be related to regulating the level of markers related to bone metabolism. |
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