| 赵 顺,王树萌,王珊珊,张 璐,秦金凤.食管癌术后患者癌因性疲乏现状调查及与社会支持和生存质量的相关性分析[J].,2022,(17):3378-3382 |
| 食管癌术后患者癌因性疲乏现状调查及与社会支持和生存质量的相关性分析 |
| Investigation on the Status of Cancer-related Fatigue in Postoperative Patients with Esophageal Cancer and Its Correlation with Social Support and Quality of life |
| 投稿时间：2022-02-27 修订日期：2022-03-23 |
| DOI：10.13241/j.cnki.pmb.2022.17.035 |
| 中文关键词: 食管癌 癌因性疲乏 社会支持 生存质量 相关性 |
| 英文关键词: Esophageal cancer Cancer-related fatigue Social support Quality of life Correlation |
| 基金项目:山东省中医药科学技术研究项目（2017-052） |
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| 中文摘要: |
| 摘要 目的：调查食管癌术后患者癌因性疲乏现状，分析其影响因素，同时观察癌因性疲乏与社会支持和生存质量的相关性。方法：选取2019年7月~2021年4月期间在我院住院治疗的食管癌术后患者180例，统计并整理所有患者的临床资料，采用社会支持评定量表（SSRS）评价所有患者的社会支持情况，采用世界卫生组织生存质量测定量表简表（WHOQOL-BREF）评价所有患者的生存质量，采用Piper疲乏量表（PFS）评价所有患者癌因性疲乏情况。应用Pearson检验分析PFS评分与SSRS评分和WHOQOL-BREF评分的相关性，采用单因素及多因素Logistic回归分析癌因性疲乏的影响因素。结果：180例食管癌术后患者共有141例发生癌因性疲乏，发生率为78.33%。根据食管癌患者术后是否发生癌因性疲乏分为两组：癌因性疲乏组（n=141）和无癌因性疲乏组（n=39）。其中癌因性疲乏组PFS评分为（6.37±1.29）分。单因素分析结果显示，食管癌术后患者癌因性疲乏与与年龄、睡眠、营养状况、疼痛程度、社会支持度、简明心境量表（POMS-SF）评分有关（P<0.05）。多因素Logistic回归分析结果显示：年龄、睡眠、营养状况、疼痛程度、社会支持度、POMS-SF评分均是食管癌术后患者癌因性疲乏的影响因素(P＜0.05)。无癌因性疲乏组SSRS各维度评分及总分和WHOQOL-BREF各维度评分及总分均高于癌因性疲乏组（P<0.05）。Pearson相关分析结果显示，PFS评分与SSRS评分和WHOQOL-BREF评分均呈负相关（P<0.05）。结论：食管癌术后患者癌因性疲乏发生率较高，且受到年龄、睡眠、营养状况、疼痛程度、社会支持度、POMS-SF评分的影响，同时还与生存质量及社会支持度具有一定联系，临床应重视相关影响因素，给予及时的干预，以预防癌因性疲乏的发生或减轻癌因性疲乏程度。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the status of cancer-related fatigue in postoperative patients with esophageal cancer, to analyze its influencing factors, and observe the relationship between cancer-related fatigue and social support and quality of life. Methods: From July 2019 to April 2021, 180 postoperative patients with esophageal cancer who were hospitalized in our hospital were selected. The clinical data of all patients were counted and sorted out. The social support of all patients was evaluated by social support rating scale (SSRS), and the quality of life of all patients was evaluated by World Health Organization quality of life scale brief (WHOQOL-BREF), the Piper Fatigue Scale (PFS) was used to evaluate cancer-related fatigue in all patients. The correlation between PFS score, SSRS score and WHOQOL-BREF score was analyzed by Pearson correlation analysis. The influencing factors of cancer-related fatigue in postoperative patients with esophageal cancer were analyzed by univariate and multivariate Logistic regression. Results: 141 cases of 180 cases of postoperative patients with esophageal cancer developed cancer-related fatigue, with an incidence of 78.33%. Patients with esophageal cancer were divided into two groups according to whether cancer-related fatigue occurred after operation: cancer-related fatigue group (n=141) and non cancer-related fatigue group (n=39). The PFS score of cancer-related fatigue group was (6.37±1.29) scores. Univariate analysis showed that postoperative cancer-related fatigue was related to age, sleep, nutritional status, pain degree, social support and POMS-SF score (P<0.05). Multivariate Logistic regression analysis showed that age, sleep, nutritional status, pain degree, social support and POMS-SF score were the influencing factors of cancer-related fatigue in postoperative patients with esophageal cancer (P<0.05). The scores and total scores of SSRS and WHOQOL-BREF in non cancer-related fatigue group were higher than those in cancer-related fatigue group (P<0.05). Pearson correlation analysis showed that PFS score were negatively correlated with SSRS score and WHOQOL-BREF score (P<0.05). Conclusion: The incidence of cancer-related fatigue is high in postoperative patients with esophageal cancer, which is affected by age, sleep, nutritional status, pain degree, social support, POMS-SF score, and is also associated with quality of life and social support. Clinical attention should be paid to the relevant factors, and timely early intervention should be given to prevent cancer-related fatigue or reduce the degree of cancer-related fatigue. |
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