| 赵智强,刘存存,陈 欢,马景旭,刘 莹.胶质瘤中CT联合MR动态扫描的诊断价值及其表观弥散系数的定量研究[J].,2022,(16):3061-3064 |
| 胶质瘤中CT联合MR动态扫描的诊断价值及其表观弥散系数的定量研究 |
| The Diagnostic Value of CT Combined with MR Dynamic Scanning in Glioma and the Quantitative Study of Apparent Diffusion Coefficient |
| 投稿时间：2021-11-23 修订日期：2021-12-18 |
| DOI：10.13241/j.cnki.pmb.2022.16.013 |
| 中文关键词: 电子计算机断层扫描 核磁共振 表观弥散系数 胶质瘤 |
| 英文关键词: Computed tomography Nuclear magnetic resonance Apparent diffusion coefficient Glioma |
| 基金项目:新疆维吾尔自治区卫生健康青年医学科技人才专项科研项目（WJWY-202209） |
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| 中文摘要: |
| 摘要 目的：探讨胶质瘤中电子计算机断层扫描（CT）联合核磁共振（MR）动态扫描的诊断价值及其表观弥散系数（ADC）定量价值，以促进胶质瘤的有效早期诊断。方法：2017年4月到2021年3月选择在本院进行诊治的颅内肿瘤患者68例作为研究对象，所有患者均给予CT联合MR动态扫描，记录ADC值并判断诊断价值。结果：在68例患者中，病理诊断为胶质瘤38例（胶质瘤组），非胶质瘤30例（非胶质瘤组）。胶质瘤组的CT出血、水肿、跨中线、界限不清等特征与非胶质瘤组对比差异有统计学意义（P<0.05）。胶质瘤组多表现为T1WI低信号、T2WI高信号，非胶质瘤组多表现为T1WI等信号或低信号、T2WI高信号，对比差异有统计学意义（P<0.05）。胶质瘤组的MR ADCmax、ADCmedian、ADCmin都低于非胶质瘤组（P<0.05）。胶质瘤中CT联合MR动态扫描诊断为胶质瘤37例，非胶质瘤31例，CT联合MR动态扫描诊断胶质瘤的敏感性与特异性为97.4 %（37/38）和100.0 %（30/30）。结论：CT联合MR动态扫描诊断胶质瘤具有很好的敏感性与特异性，ADC值能有效反映病灶组织的病理特征，为临床上提供了一种较为安全、有效的胶质瘤影像检查方法。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the diagnostic valueS of Computed Tomography (CT) combined with Magnetic Resonance(MR) dynamic scanning and the quantitative value of apparent diffusion coefficient (ADC) in the diagnosis of glioma. Methods: From April 2017 to March 2021, 68 cases of patients with intracranial tumors who were diagnosed and treated in our hospital were selected as the research objects. All patients were given CT combined with MR dynamic scans, recorded the ADC value and judged the diagnostic value. Results: There were 38 cases were pathologically diagnosed as glioma (glioma group), and 30 cases of non-glioma (non-glioma group) in the 68 cases. The CT hemorrhage, edema, cross-midline, boundary, unclear features compared between the glioma group and the non-glioma group were differences (P<0.05). The glioma group were mostly showed low signal on T1WI and high signal on T2WI, while the non-glioma group were showed mostly low signal on T1WI or low signal and high signal on T2WI., compared the difference were statistically significant(P<0.05). The MR ADCmax, ADCmedian and ADCmin of the glioma group were lower than those of the non-glioma group(P<0.05). There were 37 cases of glioma were diagnosed by CT combined with MR dynamic scanning, and 31 cases were non-glioma. The sensitivity and specificity of CT combined with MR dynamic scanning in the diagnosis of glioma were 97.4% (37/38) and 100.0% (30/30). Conclusion: CT combined with MR dynamic scanning have good sensitivity and specificity in the diagnosis of glioma. ADC value can effectively reflect the pathological characteristics of the lesion tissue, providing safe and effective clinical imaging method for glioma. |
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