| 张 丹,孙秀云,周丽娜,刘诗宇,刘 强,周 云.盆底肌肉康复训练联合盆底重建术对女性盆底功能障碍性疾病患者炎症反应及应激反应的影响[J].,2022,(1):187-191 |
| 盆底肌肉康复训练联合盆底重建术对女性盆底功能障碍性疾病患者炎症反应及应激反应的影响 |
| Effects of Pelvic Floor Muscle Rehabilitation Training Combined with Pelvic Floor Reconstruction on Inflammatory Response and Stress Response in Female Pelvic Floor Dysfunction |
| 投稿时间：2021-06-23 修订日期：2021-07-17 |
| DOI：10.13241/j.cnki.pmb.2022.01.036 |
| 中文关键词: 盆底肌肉康复训练 盆底重建术 盆底功能障碍性疾病 炎症反应 应激反应 |
| 英文关键词: Pelvic floor muscle rehabilitation training Pelvic floor reconstruction Pelvic floor dysfunction Inflammatory response Stress response |
| 基金项目:2021年吴阶平基金项目（320.6750.2021-12-1） |
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| 中文摘要: |
| 摘要 目的：观察盆底肌肉康复训练联合盆底重建术治疗女性盆底功能障碍性疾病（PFD）的疗效及对炎症反应及应激反应的影响。方法：选择2019年1月~2021年1月期间我院收治的PFD患者200例，按乱数表法分为对照组（100例）和研究组（100例）。对照组患者接受盆底重建术治疗，研究组患者接受盆底肌肉康复训练联合盆底重建术治疗。观察两组治疗后的疗效及术后并发症发生情况，对比两组相关量表评分、炎症反应及应激反应指标。结果：研究组治疗后盆底功能影响问卷简表（PFIQ-7）、盆底不适调查表简表（PFDI-20）评分低于对照组（P<0.05）。研究组治疗后盆底Ⅰ类肌纤维肌电压、盆底Ⅱ类肌纤维肌电压高于对照组（P<0.05）。研究组治疗后白介素-6（IL-6）、肿瘤坏死因子-α（TNF-α）、超敏C反应蛋白（hs-CRP）低于对照组（P<0.05）。研究组治疗后皮质醇(COR)、去甲肾上腺素(NE)、前列腺素E2(PGE2)低于对照组（P<0.05）。研究组术后并发症发生率低于对照组（P<0.05）。结论：盆底肌肉康复训练联合盆底重建术治疗PFD，可促进盆底功能恢复，减轻机体炎症反应及应激反应，降低术后并发症发生率。 |
| 英文摘要: |
| ABSTRACT Objective: To observe the efficacy of pelvic floor muscle rehabilitation training combined with pelvic floor reconstruction in the treatment of female pelvic floor dysfunction (PFD) diseases and its effect on inflammatory response and stress response. Methods: 200 patients with PFD who were treated in our hospital from January 2019 to January 2021 were selected, and they were randomly divided into control group (100 cases) and study group (100 cases) by random number table method. Patients in the control group received pelvic floor reconstruction, and patients in the study group received pelvic floor muscle rehabilitation training combined with pelvic floor reconstruction. The efficacy and postoperative complications of the two groups were observed, and the related scale scores, inflammatory response and stress response indexes of the two groups were compared. Results: After treatment, the scores of pelvic floor impact questionnaire short form (PFIQ-7), pelvic floor distress inventory short form (PFDI-20) in the study group were lower than those in the control group (P<0.05). The pelvic floor class I muscle fiber voltage and pelvic floor class II muscle fiber voltage in the study group were higher than those in the control group after treatment (P<0.05). Interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) and high sensitivity C-reactive protein (hs-CRP) in the study group after treatment were lower than those in the control group (P<0.05). Cortisol (COR), norepinephrine (NE) and prostaglandin E2 (PGE2) in the study group after treatment were lower than those in the control group (P<0.05). The incidence of postoperative complications in the study group was lower than that in the control group (P<0.05). Conclusion: Pelvic floor muscle rehabilitation training combined with pelvic floor reconstruction in the treatment of PFD can promote the recovery of pelvic floor function, reduce inflammatory reaction and stress reaction, and reduce the incidence of postoperative complications. |
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