文章摘要
胡卫红,丁燕莉,施于超,向 伟,钱时兴,陆光华.长期住院老年精神疾病患者营养状况与认知功能的相关性研究[J].,2022,(1):118-121
长期住院老年精神疾病患者营养状况与认知功能的相关性研究
Correlation Study Between Nutritional Status and Cognitive Function of Long-term Hospitalized Elderly Patients with Mental Diseases
投稿时间:2021-07-27  修订日期:2021-08-23
DOI:10.13241/j.cnki.pmb.2022.01.021
中文关键词: 老年  精神疾病  营养状况  认知功能  相关性
英文关键词: Elderly  Mental diseases  Nutrition status  Cognitive function  Correlation
基金项目:上海市卫生和计划生育委员会科研课题(s2018-641)
作者单位E-mail
胡卫红 上海交通大学医学院附属精神卫生中心老年二科 上海 201108 hwhongqh@163.com 
丁燕莉 上海交通大学医学院附属精神卫生中心老年二科 上海 201108  
施于超 上海交通大学医学院附属精神卫生中心老年二科 上海 201108  
向 伟 上海交通大学医学院附属精神卫生中心老年二科 上海 201108  
钱时兴 上海交通大学医学院附属精神卫生中心老年二科 上海 201108  
陆光华 上海交通大学医学院附属精神卫生中心老年二科 上海 201108  
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中文摘要:
      摘要 目的:了解长期住院老年精神疾病患者营养状况及与认知功能的相关性,为临床提供指导。方法:对住院3个月及以上的123例老年精神疾病患者采用简易精神状态检查量表(MMSE)评估认知功能,采用简易微型营养评定精简版(MNA-SF)评估营养状况,并采集一般资料、相关营养生化指标,应用Pearson相关分析MNA-SF评分与MMSE评分的相关性。结果:123例患者中,营养不良风险者67例(54.47%),营养不良者37例(30.08%),营养正常者19例(15.44%)。有认知障碍患者的营养不良发生率显著高于无认知障碍患者营养不良发生率(P<0.05),重度认知障碍者营养不良发生率显著高于轻、中度认知障碍者(P<0.05)。与无认知障碍者比较,中度、重度认知障碍者MNA-SF评分显著降低(P<0.05);与轻度、中度认知障碍者比较,重度认知障碍者MNA-SF评分显著降低(P<0.05)。营养不良者MMSE 6个认知领域评分和认知总评分均显著低于营养不良风险/正常者(P<0.05),Pearson相关分析显示: 长期住院老年精神疾病患者MNA-SF评分与MMSE评分呈正相关(r=0.486, P=0.023<0.05)。结论:长期住院老年精神疾病患者营养不良发生率高,且与认知功能密切相关。临床部门需加强老年精神疾病患者,特别是有认知损害老人的营养关切。
英文摘要:
      ABSTRACT Objective: To understand the nutritional status of long-term hospitalized elderly patients with mental diseases and its correlation with cognitive function, so as to provide guidance for clinical practice. Methods: 123 elderly patients with mental diseases who were hospitalized for 3 months or more were assessed for cognitive function by mini-mental state examination scale (MMSE), the nutritional status was assessed by short-form mini nutritional assessment (MNA-SF), general data and related nutritional biochemical indexes were collected, and Pearson correlation was used to analyze the correlation between MNA-SF score and MMSE score. Results: Among the 123 patients, 67 cases (54.47%) were at risk of malnutrition, 37 cases (30.08%) were malnourished, and 19 cases (15.44%) were normal nutritionist. The incidence of malnutrition in patients with cognitive impairment was significantly higher than that in patients without cognitive impairment (P<0.05). The incidence of malnutrition in patients with severe cognitive impairment was significantly higher than that in patients with mild and moderate cognitive impairment (P<0.05). Compared with those without cognitive impairment, the MNA-SF score of patients with moderate and severe cognitive impairment decreased significantly (P<0.05). Compared with mild and moderate cognitive impairment, the MNA-SF score of severe cognitive impairment was significantly lower (P<0.05). The scores of 6 cognitive domains and total cognitive scores of MMSE in malnutrition patients were significantly lower than those in malnutrition risk/normal patients (P<0.05). Pearson correlation analysis showed that there was a positive correlation between MNA-SF score and MMSE score (r=0.486, P=0.023<0.05). Conclusion: The incidence of malnutrition in long-term hospitalized elderly patients with mental diseases is high, which is closely related to cognitive function. Clinical departments need to strengthen the nutritional concerns of elderly patients with mental diseases, especially those with cognitive impairment.
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