| 藏琳琳,杨 磊,赵春月,董雪梅,周业平.封闭式负压引流术联合自体游离皮片植皮治疗四肢皮肤软组织感染创面的疗效观察[J].,2022,(1):94-98 |
| 封闭式负压引流术联合自体游离皮片植皮治疗四肢皮肤软组织感染创面的疗效观察 |
| Clinical Observation of Vacuum Sealing Drainage Combined with Free Skin Grafting in the Treatment of Limb Skin and Soft Tissue Infection Wound |
| 投稿时间：2021-06-23 修订日期：2021-07-18 |
| DOI：10.13241/j.cnki.pmb.2022.01.016 |
| 中文关键词: 封闭式负压引流术 自体游离皮片植皮 四肢皮肤软组织感染创面 疗效 疼痛 并发症 |
| 英文关键词: Vacuum sealing drainage Free autologous skin graft Llimb skin and soft tissue infection wound Efficacy Pain Complication |
| 基金项目:北京市优秀人才培养资助项目（20051d0300205） |
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| 中文摘要: |
| 摘要 目的：探究封闭式负压引流术（VSD）联合自体游离皮片植皮治疗四肢皮肤软组织感染创面的疗效及其对疼痛的影响。方法：选择2018年12月-2020年10月北京积水潭医院收治的四肢皮肤软组织感染创面患者90例，按随机数字表法将其分为对照组和观察组，每组45例。对照组采用传统的治疗方法治疗，观察组采用VSD联合自体游离皮片植皮治疗。对比两组治疗结束后的临床疗效，并观察两组治疗前以及治疗后24 h、3 d的疼痛程度，对比两组一般治疗情况及治疗过程中的不良反应。结果：观察组治疗总有效率为93.33%，显著高于对照组的68.89%，差异有统计学意义（P<0.05）。两组患者在治疗后24 h和3 d的数字疼痛量表（NRS）评分低于治疗前，治疗后3 d NRS疼痛评分低于治疗后24 h（均P<0.05），且治疗后24 h和3 d观察组NRS疼痛评分均显著低于对照组（P均<0.05）。观察组患者并发症的发生率为31.11%，明显低于对照组的57.78%，差异有统计学意义（P<0.05）。观察组换药频率显著低于对照组，且疼痛暂缓时间、创面愈合时间、住院时间更短，差异具有统计学意义（P<0.05）。结论：VSD联合自体游离皮片植皮有利于提高治疗四肢皮肤软组织感染创面的临床疗效，缓解患者疼痛症状，并降低并发症发生率。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the effect of closed negative pressure drainage (VSD) combined with free autologous skin graft in the treatment of limb skin and soft tissue infection wound and its effect on pain. Methods: 90 cases of limb skin and soft tissue infection wound in Beijing Jishuitan Hospital from December 2018 to October 2020 were selected and randomly divided into control group and observation group, 45 cases in each group. The control group was treated with traditional treatment, and the observation group was treated with VSD combined with free autologous skin graft. The clinical efficacy of the two groups after treatment was compared, and the pain degree before treatment and 24 h and 3 d after treatment were observed, and the general treatment situation and adverse reactions in the treatment process were compared between the two groups. Results: The total effective rate of the observation group was 93.33%, which was significantly higher than 68.89% of the control group (P<0.05). The NRS scores at 24 h and 3 d after treatment were lower than those before treatment, and those at 3 d after treatment were lower than those at 24 h after treatment (all P<0.05), and the NRS pain scores at 24 h and 3 d after treatment in the observation group were significantly lower than those in the control group (all P<0.05). The incidence of complications in the observation group was 31.11%, which was significantly lower than 57.78% of the control group (P<0.05). The dressing change frequency of the observation group was significantly lower than that of the control group, and the duration of pain relief, wound healing time and length of stay were shorter, the difference was statistically significant (P<0.05). Conclusion: VSD combined with free autologous skin graft is conducive to improve the clinical efficacy of the treatment of limb skin and soft tissue infection wound, relieve the pain symptoms of patients, and reduce the incidence of complications. |
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