| 黄文辉,赵玲莉,李 娟,何轶群,雷海娟,史俊莲.维生素A、E水平与儿童反复呼吸道感染的相关性和危险因素研究[J].,2021,(22):4377-4381 |
| 维生素A、E水平与儿童反复呼吸道感染的相关性和危险因素研究 |
| Correlation and Risk Factors of Vitamin A and E Levels with Recurrent Respiratory Tract Infection in Children |
| 投稿时间：2021-04-23 修订日期：2021-05-18 |
| DOI：10.13241/j.cnki.pmb.2021.22.037 |
| 中文关键词: 儿童反复呼吸道感染 维生素A 维生素E 相关性 危险因素 |
| 英文关键词: Recurrent respiratory tract infection in children Vitamin A Vitamin E Relevance Risk factor |
| 基金项目:科技部科技基础资源调查专项项目（2019FY101200） |
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| 中文摘要: |
| 摘要 目的：研究维生素A（VA）、维生素E（VE）水平与儿童反复呼吸道感染（RRI）的相关性和危险因素。方法：选择本院2017年1月~2019年10月诊治的318例RRI患儿，同期选择285例健康体检儿童作为对照组，比较各组VA、VE表达情况，并分析儿童RRI发生的危险因素。结果：RRI组VA及VE水平低于对照组，VA及VE缺乏率高于对照组，差异有统计学意义（P<0.05）。1~3岁患儿VA及VE水平高于3~6岁组且高于>6岁组（P<0.05）。对照组和RRI组性别、出生时体重比较无统计学差异（P>0.05）；RRI组自然分娩、母乳喂养率低于对照组，偏食、过敏体质、抗生素滥用、人均居住面积<13 m2、母亲文化高中及以下率高于对照组（P<0.05）。多因素Logistic回归分析显示，早产、偏食、过敏体质、被动吸烟、抗生素滥用、人均居住面积<13 m2是RRI发生的独立危险因素，VA、VE、自然分娩、母乳喂养、母亲文化程度是RRI发生的保护因素。结论：RRI儿童VA、VE水平较低，且RRI的发生和多种危险因素相关，临床应针对性的进行预防干预。 |
| 英文摘要: |
| ABSTRACT Objective: To study the correlation and risk factors between vitamin A(VA) and vitamin E(VE) levels and recurrent respiratory tract infection (RRI) in children. Methods: 318 RRI children diagnosed and treated in our hospital from January 2017 to October 2019 were selected, 285 healthy children were selected as control group at the same time. The expressions of VA and VE in each group were compared and the risk factors of RRI in children were analyzed. Results: The VA and VE leVEls in RRI group were lower than those in the control group, and the VA and VE deficiency rates were higher than those in the control group, the difference was statistically significant(P<0.05). VA and VE levels of children aged 1-3 years old were higher than those of 3-6 years old group and higher than those of >6 years old group(P<0.05). There was no significant difference in sex and birth weight between control group and RRI group (P>0.05). The rates of natural delivery and breast feeding in RRI group were lower than those in the control group, and the rates of partial diet, allergic constitution, antibiotic abuse, per capita living area < 13 m2, mother's cultural high school and below were higher than those in the control group(P<0.05). Multivariate Logistic regression analysis showed that premature birth, partial diet, allergic constitution, passiVE smoking, antibiotic abuse and per capita living area <13 m2 were independent risk factors for RRI, while VA, VE, natural childbirth, breast feeding and mother's educational level were protective factors for RRI. Conclusion: The levels of VA and VE in RRI children are relatively low, and the occurrence of RRI is related to various risk factors. Therefore, clinical prevention and intervention should be targeted. |
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