| 蒋 煊,褚海婷,贾灿萍,柏斗胜,陆世春.慢性阻塞性肺疾病患者超声监测膈肌增厚率与肺功能的相关性[J].,2021,(20):3903-3906 |
| 慢性阻塞性肺疾病患者超声监测膈肌增厚率与肺功能的相关性 |
| The Correlation between the Diaphragm Thickening Rate and Lung Function in Patients with Chronic Obstructive Pulmonary Disease |
| 投稿时间：2021-02-05 修订日期：2021-02-28 |
| DOI：10.13241/j.cnki.pmb.2021.20.020 |
| 中文关键词: 慢性阻塞性肺疾病 膈肌增厚率 肺功能 超声监测 呼气流量峰值 相关性 危险因素 |
| 英文关键词: Chronic obstructive pulmonary disease Diaphragm thickening rate Lung function Ultrasound monitoring Peak expiratory flow Correlation Risk factors |
| 基金项目:国家自然科学基金面上项目（81871909） |
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| 中文摘要: |
| 摘要 目的：探讨慢性阻塞性肺疾病(Chronic obstructive pulmonary disease，COPD)患者超声监测膈肌增厚率与肺功能的相关性。方法：2019年1月到2020年12月选择在本院诊治的COPD患者72例作为COPD组，同期选择在本院体检的健康人72例作为对照组。采用超声监测两组入选者的膈肌增厚率，使用肺功能测定仪测定呼气流量峰值(peak expiratory flow，PEF)、第1 秒用力呼气容积占预计值百分比(Forced Expiratory Volume in the first second，FEV1)、肺活量25 %时用力呼气流速(Vmax25%，V25)、肺活量50 %时用力呼气流速(Vmax50%，V50)、肺活量75 %时用力呼气流速(Vmax75%，V75)等指标并进行相关性分析。结果：COPD组的膈肌增厚率低于对照组，对比差异有统计学意义(P<0.05)。COPD组的FEV1、PEF、V25、V50、V75值都低于对照组，对比差异都有统计学意义(P<0.05)。在COPD组患者中，Pearson相关分析显示膈肌增厚率与FEV1、PEF、V25、V50、V75都存在正相关性(P<0.05)。Logistic回归分析显示FEV1、PEF、V25、V50、V75为影响膈肌增厚率的重要影响因素P<0.05)。结论：COPD患者超声监测可显示膈肌增厚率与肺功能降低，两者存在相关性，肺功能下降也是导致患者膈肌增厚率降低的重要危险因素。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the correlation between ultrasound monitoring of diaphragm thickening rate and lung function in patients with chronic obstructive pulmonary disease (COPD). Methods: From January 2019 to December 2020, 72 cases of patients with COPD who were diagnosed and treated in this hospital were selected as the COPD group, and the other 72 cases healthy people who given physical examination in this hospital during the same period were selected as the control group. Ultrasound were used to monitor the diaphragm thickening rate of the two groups, and the pulmonary function tester were used to measure the peak expiratory flow (PEF), Forced Expiratory Volume in the first second (FEV1), Vmax25 %(V25), Vmax50 %(V50),Vmax75 %(V75), et al. and were given correlation analysis. Results: The thickening rate of diaphragm in the COPD group were lower than that in the control group (P<0.05). The FEV1, PEF, V25, V50, and V75 values of the COPD group were lower than those of the control group that compared the difference were statistically significant(P<0.05). In the COPD group, Pearson correlation analysis showed that the rate of diaphragmatic muscle thickening were positively correlated with FEV1, PEF, V25, V50, and V75 that compared the difference were statistically significant(P<0.05). Logistic regression analysis showed that FEV1, PEF, V25, V50, and V75 were important factors affected the thickening rate of the diaphragm (P<0.05). Conclusion: Ultrasound monitoring of COPD patients can show that the rate of diaphragmatic muscle thickening is correlated with the decrease of lung function. Decreased lung function are also important risk factors lead to the decrease of diaphragmatic muscle thickening rate. |
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