| 陈 妍,左 婧,李雅静,艾荣梅,王 旺.穴位敷贴联合妇科千金片对湿热蕴结型盆腔炎后遗症患者盆腔血流动力学、炎症因子和生活质量的影响[J].,2021,(19):3792-3795 |
| 穴位敷贴联合妇科千金片对湿热蕴结型盆腔炎后遗症患者盆腔血流动力学、炎症因子和生活质量的影响 |
| Effect of Acupoint Application Combined with Fuke Qianjin Tablet on Pelvic Hemodynamics, Inflammatory Factors and Quality of Life in Patients with Sequelae of Pelvic Inflammatory Disease of Damp Heat Accumulation Type |
| 投稿时间：2021-02-21 修订日期：2021-03-16 |
| DOI：10.13241/j.cnki.pmb.2021.19.040 |
| 中文关键词: 穴位敷贴 妇科千金片 湿热蕴结型 盆腔炎后遗症 血流动力学 炎症因子 生活质量 |
| 英文关键词: Acupoint application Fuke Qianjin tablet Damp heat accumulation type Sequelae of pelvic inflammatory disease Hemodynamics Inflammatory factors Quality of life |
| 基金项目:江苏省高层次卫生人才"六个一工程"项目（LGY2016027） |
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| 中文摘要: |
| 摘要 目的：观察穴位敷贴联合妇科千金片对湿热蕴结型盆腔炎后遗症患者盆腔血流动力学、炎症因子和生活质量的影响。方法：本次研究选取的病例来源于2018年3月~2020年8月期间我院收治的107例盆腔炎后遗症患者，采用随机数字表法将患者分为对照组（53例，基础治疗联合妇科千金片）和实验组（54例，对照组的基础上联合穴位敷贴治疗），两组均以1个月经周期为1个疗程，治疗2个疗程。对比两组中医疗效、中医证候、血流动力学[阻力指数（RI）、搏动指数（PI）、最大血流速度（PSV）]、炎症因子[C反应蛋白（CRP）、白介素-6（IL-6）、肿瘤坏死因子-α（TNF-α）]和生活质量。结果：实验组治疗2个疗程后（治疗后）的中医临床总有效率高于对照组（P<0.05）。两组治疗后中医证候积分和血清CRP、IL-6、TNF-α水平以及RI降低，且实验组低于对照组（P<0.05）。两组治疗后健康状况、生存质量、日常活动、自我感觉、总分以及PI、PSV升高，且实验组高于对照组（P<0.05）。结论：穴位敷贴联合妇科千金片治疗湿热蕴结型盆腔炎后遗症患者，可有效改善其临床症状，降低炎症因子水平，改善机体血流动力学，并提高其生活质量，疗效显著。 |
| 英文摘要: |
| ABSTRACT Objective: To observe the effect of acupoint application combined with Fuke Qianjin tablet on pelvic hemodynamics, inflammatory factors and quality of life in patients with sequelae of pelvic inflammatory disease of damp heat accumulation type. Methods: This study selected 107 patients with sequelae of pelvic inflammatory disease in our hospital from March 2018 to August 2020, and they were randomly divided into control group (53 cases, basic treatment combined with Fuke Qianjin tablet) and experimental group (54 cases, combined with acupoint application on the basis of control group) by random number table method. Both groups were treated with one menstrual cycle as a course of treatment and two courses of treatment. The traditional Chinese medicine efficacy, traditional Chinese medicine syndromes, hemodynamics [resistance index (RI), pulsation index (PI), maximum blood flow velocity (PSV)], inflammatory factors [C reactive protein (CRP), interleukin-6(IL-6), tumor necrosis factor-α (TNF-α)] and quality of life of the two groups were compared. Results: The total effective rate of the experimental group was higher than that of the control group after two courses of treatment (after treatment)(P<0.05). After treatment, the traditional Chinese medicine syndrome score, serum CRP, IL-6, TNF-α levels and RI of the two groups were decreased, and the experimental group was lower than the control group (P<0.05). After treatment, the health status, quality of life, daily activities, self feeling, total score, PI and PSV of the two groups were increased, and the experimental group was higher than the control group(P<0.05). Conclusion: Acupoint application combined with Fuke Qianjin tablet in the treatment of patients with sequelae of pelvic inflammatory disease of damp heat accumulation type can effectively improve the clinical symptoms, reduce the inflammatory factors levels, improve the body hemodynamics, and improve the quality of life of patients, with significant curative effect. |
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