文章摘要
葛 兰,刘 莉,王 倩,郭霁萱,汤丹卉,张建军.心力衰竭患者症状群变化研究及对患者生活质量的影响[J].,2021,(19):3665-3669
心力衰竭患者症状群变化研究及对患者生活质量的影响
Study on Changes of Symptom Cluster in Patients with Heart Failure and Its Influence on Patients' Quality of Life
投稿时间:2021-05-10  修订日期:2021-05-31
DOI:10.13241/j.cnki.pmb.2021.19.013
中文关键词: 心力衰竭  症状群  生活质量  影响因素
英文关键词: Heart failure  Symptom cluster  Quality of life  Influence factor
基金项目:北京市科技计划项目(Z171100000417055)
作者单位E-mail
葛 兰 首都医科大学附属北京朝阳医院心内科 北京 100043 gelanccu@163.com 
刘 莉 首都医科大学附属北京朝阳医院心内科 北京 100043  
王 倩 首都医科大学附属北京朝阳医院心内科 北京 100043  
郭霁萱 首都医科大学附属北京朝阳医院心内科 北京 100043  
汤丹卉 首都医科大学附属北京朝阳医院心内科 北京 100043  
张建军 首都医科大学附属北京朝阳医院心内科 北京 100043  
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中文摘要:
      摘要 目的:探讨心力衰竭患者症状群的变化情况,并分析其对生活质量的影响。方法:前瞻性选取我院2018年10月~2020年10月收治的心力衰竭患者122例,分别在患者入院时及出院3后个月、6个月进行Memorial心力衰竭症状评估量表(MSAS-HF)、明尼苏达心力衰竭生活质量量表(MLHFQ)评分,分析患者MSAS-HF评分与MLHFQ评分的相关性以及患者出院后6个月生活质量的影响因素。结果:心力衰竭患者出院后3个月、6个月的疲倦、不适、情绪、淤血、缺血、呼吸困难症状群评分及总分均低于入院时,且出院后6个月的情绪症状群评分低于出院后3个月(P<0.05);心力衰竭患者出院后3个月、6个月的情绪领域、躯体领域、其他领域评分及总分低于入院时,且出院后6个月的情绪领域评分、总分低于出院后3个月(P<0.05);出院后6个月心力衰竭患者MSAS-HF各维度评分及总分与MLHFQ总分呈正相关(P<0.05);单因素分析显示:患者出院后6个月生活质量与入院时左室射血分数(LVEF)、入院时MSAS-HF总分、入院时纽约心功能分级(NYHA)、病程有关(P<0.05);Logistic多元回归分析提示:入院时LVEF≤40%、入院时NYHA Ⅳ级、病程>5年是患者出院后6个月生活质量的危险因素(P<0.05),而入院时MSAS-HF总分<40分是患者出院后6个月生活质量的保护因素(P<0.05)。结论:心力衰竭患者出院后3、6个月的症状群程度均减轻,生活质量有所改善,患者入院时症状群对生活质量有影响。
英文摘要:
      ABSTRACT Objective: To explore the changes of symptom cluster in patients with heart failure, and to analyze its influence on the quality of life. Methods: 122 patients with heart failure who were admitted to our hospital from October 2018 to October 2020 were prospectively selected. Memorial Heart Failure Symptom Assessment Scale (MSAS-HF) and Minnesota Heart Failure Quality of Life Scale (MLHFQ) were scored of patients at admission, 3 months and 6 months after discharge, respectively. The correlation between MSAS-HF score and MLHFQ score, as well as the influencing factors of patients' quality of life 6 months after discharge were analyzed. Results: The scores of fatigue, discomfort, mood, congestion, ischemia and dyspnea of patients with heart failure at 3 and 6 months after discharge were lower than those at admission, and the scores of mood symptom cluster at 6 months after discharge were lower than those at 3 months after discharge (P<0.05). The scores and total scores of emotional field, physical field and other fields of patients with heart failure at 3 months and 6 months after discharge were lower than those at admission, and the scores and total scores of emotional field at 6 months after discharge were lower than those at 3 months after discharge (P<0.05). At 6 months after discharge, the scores and total scores of MSAS-HF all dimensions were positively correlated with the total scores of MLHFQ (P<0.05). Univariate analysis showed that the quality of life at 6 months after discharge was related to the left ventricular ejection fraction (LVEF) at admission, the total score of MSAS-HF at admission, the New York heart Association (NYHA) at admission and the course of disease (P<0.05). Logistic multiple regression analysis suggested: LVEF ≤40% at admission, NYHA Ⅳ at admission, and disease course > 5 years were risk factors for 6 months after discharge of patient of life quality (P<0.05), while MSAS-HF total score < 40 scores at admission was protective factor for 6 months after discharge of patient of life quality (P<0.05). Conclusion: The symptoms of patients with heart failure are reduced at 3 and 6 months after discharge, and the quality of life is improved. The symptoms of patients at admission have an impact on the quality of life.
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