| 周 凯,胡 沥,曹洪英,唐 鹏,李 静.中性粒细胞与淋巴细胞比值在脓毒症诊断和预后中的临床价值[J].,2021,(17):3359-3362 |
| 中性粒细胞与淋巴细胞比值在脓毒症诊断和预后中的临床价值 |
| The Clinical Value of Neutrophil-lymphocyte Ratio in Diagnosis and Prognosis of Sepsis |
| 投稿时间：2020-12-23 修订日期：2021-01-18 |
| DOI：10.13241/j.cnki.pmb.2021.17.034 |
| 中文关键词: 脓毒血症 中性粒细胞淋巴细胞比值 预后 临床价值 |
| 英文关键词: Sepsis Neutrophils/lymphocyte ratio Prognosis Clinical value |
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| 中文摘要: |
| 摘要 目的：探讨中性粒细胞与淋巴细胞比值在脓毒症诊断和预后中的临床价值。方法：回顾性分析2017年1月至2020年1月于我院就诊的180例脓毒症患者的临床资料，分析其白细胞计数、中性粒细胞比、淋巴细胞比、中性粒细胞/淋巴细胞比值（Neutrophil/Lymphocyte ratio, NLR）、血肌酐、血糖、急性生理与慢性健康评分（Acute physiology and chronic health score, APACHEⅡ）与脓毒血症严重程度和预后的相关性。结果：180例患者中，与NLR比值低的患者相比，NLR比值高的患者死亡率更高，脓毒血症更严重，差异具有统计学意义（P<0.05）；单因素分析表明，APACHEⅡ评分和NLR值在存活组死亡组患者中差异显著，多因素回归分析结果表明，NLR比值和APACHEⅡ评分是脓毒血症预后和死亡的独立预测因子。结论：NLR值低是脓毒血症患者预后的保护因子，在临床工作中我们应充分重视NLR值高的脓毒血症患者。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the clinical value of neutrophil-lymphocyte ratio in the diagnosis and prognosis of sepsis. Methods: 180 patients with sepsis who sought medical care in our hospital from January 2018 to January 2020 were enrolled. Analyzing the relationship of blood routine examination, blood sugar, liver and kidney function, neutrophils/lymphocyte ratio (NLR), acute physiology and chronic health evaluation(APACHE Ⅱ) with the severity and prognosis of sepsis. Results: Among the 180 patients, compared with the patients with high NLR ratio, the patients with low NLR ratio had higher mortality and more severe sepsis, and the difference was statistically significant(P<0.05). Single factor analysis showed that the APACHE Ⅱ score and NLR value significant difference in the live group die group of patients, multiple factors regression analysis results show that the NLR ratio and APACHE Ⅱ rating is an independent predictor of prognosis of sepsis and death. Conclusion: Low NLR is a protective factor for the prognosis of patients with sepsis, and we should pay full attention to patients with high NLR in clinical work. |
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