| 陈培培,李 悦,梁 爽,付 强,李 莉.强化肠内营养对急诊重症患者血糖控制及病情转归的影响[J].,2021,(11):2073-2076 |
| 强化肠内营养对急诊重症患者血糖控制及病情转归的影响 |
| The Effect of Intensified Enteral Nutrition on Blood Sugar Control and Condition of Critically Ill Patients in Emergency Department |
| 投稿时间：2020-10-02 修订日期：2020-10-26 |
| DOI：10.13241/j.cnki.pmb.2021.11.016 |
| 中文关键词: 肠内营养 急诊重症 血糖 生化指标 并发症 |
| 英文关键词: Enteral nutrition Emergency critical illness Blood sugar Biochemical indicators Complications |
| 基金项目:国家自然科学基金项目（81760222） |
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| 中文摘要: |
| 摘要 目的：考察强化肠内营养对急诊重症患者血糖、营养状态以及并发症的影响。方法：以300例2018年4月-2020年3月就入住我院ICU的患者为研究对象，分为对照组和研究组，每组150例。对照组患者进行肠外营养支持，研究组患者予以肠内营养治疗，通过考察患者血糖、24 h胰岛素使用量、血清总蛋白(Total protein，Tp)、白蛋白(albumin，Alb)、肌酐(creatinine，Scr)以及并发症等指标，评价其对病情的影响。结果：研究组24 h内平均血糖为89.8±38.4 mg/dl，显著低于对照组的157.6±68.3 mg/dl(P＜0.05)，研究组24 h内胰岛素使用量为18.6±12.3 μ，显著低于对照组的34.7±30.6 μ(P＜0.05)。治疗前，两组患者Tp、Alb和肌酐清除率 (creatinine clearance，CCR)水平均无显著差异(P＞0.05)，治疗后，两组Tp和Alb水平显著升高，CCR水平显著降低(P＜0.05)；与对照组相比，研究组患者Tp和Alb水平显著升高，CCR水平显著降低(P＜0.05)。两组均存在不同程度的腹泻、腹胀以及上消化道出血情况，其中对照组的总发生率为23.33 %，研究组的为26.67 %，经比较，无显著差异(P＞0.05)。结论：强化肠内营养能有效改善急诊重症患者的血糖水平，改善患者的营养状态，安全性高。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effect of intensive enteral nutrition on blood sugar, nutritional status and complications of critically ill emergency patients. Methods: Taking 300 patients who were admitted to the ICU of our hospital from April 2018 to March 2020 as the research objects, they were divided into a control group and a study group, each with 150 cases. Patients in the control group received parenteral nutrition support, and patients in the study group received enteral nutrition therapy. The effects of blood glucose, 24 h insulin usage, total serum protein (Tp), albumin (Alb), creatinine (Scr) and complications, etc., were used to evaluate the impact on the disease. Results: The average blood glucose of the study group within 24 hours was 89.8±38.4 mg/dl, which was significantly lower than the control gro up's 157.6±68.3 mg/dl (P＜0.05), and the insulin usage in the study group within 24 hours was 18.6±12.3 μ, which was significantly lower than the control group 34.7±30.6 μ (P<0.05). Before treatment, there was no significant difference in the levels of Tp, Alb and CCR between the two groups of patients (P>0.05). After treatment, the levels of Tp and Alb in the two groups increased significantly, while the CCR levels decreased significantly (P<0.05). Compared with the control group, the levels of Tp and Alb in the study group were significantly increased, and the level of CCR was significantly decreased (P<0.05). There were different degrees of diarrhea, abdominal distension and upper gastrointestinal bleeding in the two groups. The total incidence of the control group was 23.33 %, and that of the study group was 26.67 %. After comparison, there was no significant difference (P>0.05). Conclusion: Intensified enteral nutrition can effectively improve the blood sugar level of critically ill patients in emergency departments, and improve the nutritional status of patients with high safety. |
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