| 王红利,龚小育,张 倩,王亚红,魏艳玲.滋肾育胎丸对早期先兆流产患者血清孕酮、β-HCG水平及血液流变学的影响[J].,2021,(5):954-957 |
| 滋肾育胎丸对早期先兆流产患者血清孕酮、β-HCG水平及血液流变学的影响 |
| Effect of Zishenyutai Pill on Serum Progesterone, β-HCG and Hemorheology in Patients with Early Threatened Abortion |
| 投稿时间：2020-06-29 修订日期：2020-07-24 |
| DOI：10.13241/j.cnki.pmb.2021.05.033 |
| 中文关键词: 早期 先兆流产 滋肾育胎丸 β-人绒毛膜促性腺激素 孕酮 血液流变学 |
| 英文关键词: Early stage Threatened abortion Zishenyutai pill β-HCG Progesterone Hemorheology |
| 基金项目:陕西省科学技术研究发展计划项目(2015SF0617) |
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| 中文摘要: |
| 摘要 目的：探讨滋肾育胎丸对早期先兆流产患者血清孕酮、β-人绒毛膜促性腺激素（β-HCG）水平及血液流变学的影响。方法：选取2018年1月-2020年1月我院收治的早期先兆流产患者100例，按随机数字表法分为对照组和观察组各50例。对照组给予常规西医治疗，观察组在对照组基础上给予滋肾育胎丸治疗，治疗2周后观察两组治疗前后血清孕酮、β-HCG水平、高切全血黏度、纤维蛋白原以及红细胞比容，并比较两组临床疗效及不良反应。结果：治疗2周后，两组患者血清孕酮、β-HCG水平均高于治疗前，且观察组高于对照组（P<0.05）。观察组总有效率为92.00%（46/50），明显高于对照组的74.00%（37/50），差异有统计学意义（P<0.05）。两组患者治疗2周后高切全血黏度、纤维蛋白原均较治疗前降低，且观察组低于对照组（P<0.05）；两组患者治疗前后、两组组间红细胞比容比较差异无统计学意义（P>0.05）。两组不良反应发生率比较差异无统计学意义（P>0.05）。结论：滋肾育胎丸治疗早期先兆流产患者疗效确切，能够提高血清孕酮、β-HCG水平，改善患者血液流变学，且安全性较好，值得临床推广。 |
| 英文摘要: |
| ABSTRACT Objective: To study the effect of Zishenyutai Pill on serum progesterone, β-HCG and hemorheology in patients with early threatened abortion. Methods: From January 2018 to January 2020, 100 patients with early threatened abortion in our hospital were selected and divided into control group and observation group according to the method of random number table,50 cases in each group.The control group was treated with conventional western medicine, and the observation group was treated with Zishenyutai Pill on the basis of the control group. After 2 weeks of treatment, the levels of serum progesterone, β-HCG, high cut whole blood viscosity, fibrinogen and hematocrit of the two groups were observed before and after treatment, and the clinical effects and adverse reactions of the two groups were compared. Results: 2 weeks after treatment, the levels of serum progesterone and β-HCG in the two groups were higher than those before treatment, and the level in the observation group was higher than that in the control group(P<0.05). The total effective rate of the observation group was 92.00% (46/50), which was significantly higher than 74.00% (37/50) of the control group, the difference was statistically significant (P<0.05). After 2 weeks of treatment, the high cut whole blood viscosity and fibrinogen of the two groups were lower than those before treatment, and the observation group was lower than the control group (P<0.05), while there was no significant difference in hematocrit between the two groups before and after treatment(P>0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Zishenyutai pill is effective in the treatment of early threatened abortion.It can improve the level of serum progesterone and β-HCG, and improve the hemorheology of patients. It is safe and worthy of clinical application. |
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