| 杜 玲,严玲华,诸益华,张 磊,罗国君.急性脑梗死患者医院感染临床特点与影响因素分析[J].,2021,(5):871-875 |
| 急性脑梗死患者医院感染临床特点与影响因素分析 |
| The Clinical Characteristics and Influencing Factors of Nosocomial Infection in Patientswith Acute Cerebral Infarction |
| 投稿时间：2020-06-23 修订日期：2020-07-18 |
| DOI：10.13241/j.cnki.pmb.2021.05.014 |
| 中文关键词: 急性脑梗死 医院感染 临床特点 影响因素 |
| 英文关键词: Acute Cerebral Infarction Nosocomial Infection Clinical Features Influencing Factors |
| 基金项目:上海市卫生健康委员会科研项目（201940262） |
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| 中文摘要: |
| 摘要 目的：探讨急性脑梗死患者医院感染临床特点及影响因素。方法：回顾性分析我院2018年1月至2019年12月诊断为急性脑梗死1175例患者临床资料，通过感染标本的培养及鉴定结果分析，探讨医院感染的病原菌种类及比例，进一步分析引起医院感染的危险因素。结果：1175例急性脑梗死患者中，发生医院感染99例，感染率8.4%；最常见感染部位为呼吸系统和泌尿系统；发生医院感染的99例临床标本微生物学培养及鉴定发现革兰氏阴性菌59例，革兰氏阳性菌37例，真菌3例，分别占比59.60%、37.37%及3.03%；发生医院感染的独立影响因素包括：年龄≥ 80岁、反复发作史、住院期间行气管插管、血清白蛋白<30 g/L、25－羟维生素D3<20 ng/mL，既往有慢性阻塞性肺病、NIHSS≥6。结论：急性脑梗死患者医院感染发生以呼吸道及泌尿道感染最常见，诸多因素可以引起医院感染发生，重视侵入性操作的管理外，对于营养不良等也要引起重视，从而降低医院感染率。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the clinical characters and associated risk factors of nosocomial infection in patients with acute cerebral infarction. Methods: The clinical data of 1175 patients with acute cerebral infarction were collected from January 2018 to December 2019 in our hospital. The specimens of infected sites were collected, cultured and identified to explore the types and proportions of pathogens in nosocomial infections, the risk factors affecting the nosocomial infection were further analyzed. Results: There were 99 cases of nosocomial infection in 1175 patients with an infection rate of 8.4%. The respiratory system and urinary system were the dominant sites of nosocomialinfection. Of all the nosocomial infection samples, 59 strains of gram-negativebacteria accounting for 59.60%, 37 strains of gram-positive bacteria accounting for 37.37%, and 3 strains of fungus accounting for 3.03%. The independent influencing factor that affect nosocomial infections of patients with acute cerebral infarction including age nary system were the dominant sites of nosocomial infection. Of all the nosocomial infection samples, 59 strains portions min D3 <20 ng/mL, previous chronic obstructive pulmonary disease history, NIHSS score≥6. (P<0.05). Conclusion: Patients with acute cerebral infarction is related to high risk of nosocomial infection, and respiratory and urinary systeminfections are the most common sites, a variety of independent risks contributed to nosocomial infection, corresponding preventive measures should be taken for those high-risk factors to attenuate the rate of nosocomial infection. |
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