| 辛肇晨,吴 茜,方昭然,耿盛凯,张宏伟.Luminal A型和Luminal B型乳腺癌患者的腋窝淋巴结转移发生率及预后的比较研究[J].,2021,(5):846-849 |
| Luminal A型和Luminal B型乳腺癌患者的腋窝淋巴结转移发生率及预后的比较研究 |
| A Comparative Study on the Incidence and Prognosis of Axillary Lymph Node Metastasis in Luminal Type A and Luminal Type B Breast Cancer Patients |
| 修订日期：2020-07-25 |
| DOI：10.13241/j.cnki.pmb.2021.05.009 |
| 中文关键词: 乳腺癌 Luminal A型 Luminal B型 腋窝淋巴结 转移 预后 |
| 英文关键词: Breast cancer Luminal type A Luminal type B Axillary lymph node Metastasis Prognosis |
| 基金项目:上海市科委科研项目（17104930411） |
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| 中文摘要: |
| 摘要 目的：对比Luminal A型和Luminal B型乳腺癌患者的腋窝淋巴结转移发生率及预后情况。方法：回顾性分析我院从2011年5月～2014年12月收治的乳腺癌患者180例作为研究对象。将其按照临床病理类型的差异分成Luminal A型组84例与Luminal B型组96例。比较两组临床病理特征、腋窝淋巴结转移发生率、5年复发率与生存率，比较两组患者超声学特征。结果：Luminal A型组年龄>50岁、肿瘤大小≤2 cm、组织分级Ⅰ级人数占比均高于Luminal B型组（P<0.05）。Luminal A型组腋窝淋巴结转移发生率为13.10%（11/84），显著低于Luminal B型组的39.58%（38/96）（P<0.05）。Luminal A型组和Luminal B型组患者的5年复发转移率对比差异无统计学意义（P>0.05），Luminal A型组5年生存率为86.90%（73/84），高于Luminal B型组的73.96%（71/96）（P<0.05）。Luminal A型组边界清晰、无钙化人数占比均高于Luminal B型组，而Alder为Ⅲ级人数占比低于Luminal B型组（P<0.05）。结论：Luminal A型乳腺癌患者的腋窝淋巴结转移发生率低于Luminal B型乳腺癌患者，且两者的临床病理和超声学特征存在一定的差异，Luminal A型乳腺癌患者的预后优于Luminal B型。 |
| 英文摘要: |
| ABSTRACT Objective: To compare the incidence and prognosis of axillary lymph node metastasis in Luminal type A and Luminal type B breast cancer patients. Methods: A retrospective analysis was performed on 180 cases of breast cancer who were admitted to our hospital from May 2011 to December 2014 as an object of study. According to the differences of clinicopathological types, they were divided into two groups: 84 patients in Luminal type A group and 96 patients in Luminal type B group. The clinicopathological features, incidence of axillary lymph node metastasis, 5-year recurrence rate and survival rate of the two groups were compared. In addition, the ultrasonic characteristics of the two groups of patients were compared. Results: Luminal type A group age> 50 years old, and tumor size≤2 cm, organize class Ⅰ number proportion were significantly higher than that of Luminal type B group (P<0.05). The incidence of axillary lymph node metastasis in Luminal type A group was 13.10% (11/84), which was significantly lower than 39.58% (38/96) in Luminal type B group (P<0.05). There were no significant differences in 5-year recurrence and metastasis rate between Luminal type A group and Luminal type B group (P>0.05). The 5-year survival rate in Luminal type A group was 86.90% (73/84), which was significantly higher than 73.96% (71/96) in Luminal type B group (P<0.05). The boundary clear, no calcification in Luminal type A group were higher than those in Luminal type B group, and Alder Ⅲ grade number proportion was lower than that in Luminal type B group (P<0.05). Conclusion: The incidence of axillary lymph node metastasis in Luminal A type breast cancer patients is lower than that in Luminal type B breast cancer patients, and there are some differences in clinicopathological and ultrasonic characteristics, and The prognosis of luminal type A breast cancer is better than that of luminal type B breast cancer. |
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