Objective To investigate the effect of laparoscopic surgery on elderly patients with colon cancer. Methods Taking 85 elderly colon cancer surgery patients in our hospital from June 2017 to July 2018 as the research object, according to the different surgical methods, 43 cases were divided into the A group and 42 cases the B group; The A group was given laparotomy, and the B group was given laparoscopy; The related indicators of the two groups were compared.Results The intraoperative blood loss (83.26±25.47) and anal exhaust time (56.24) of the B group ±13.26), lymph node dissection time (22.57±7.54), hospitalization time (8.84±4.46) compared with the A group (129.36±49.31, 79.41±22.15, 23.32±8.46, 11.36±5.78) were significantly lower (P<0.05). On the 1st day after operation, the IL-6 (6.54±1.02 ng/L), CRP (31.87±5.74 mg/L) in the B group compared with the A group (8.16±1.14 ng/L, 50.84±7.63 mg/L)were significant differences (P< 0.05). Three months after the operation, the CD4+ (44.28±5.23%), CD8+ (35.27±4.58%) in the B group compared with the A group (40.03±5.72%, 30.24±4.26%) were significant differences (P<0.05). The incidence of complications in the B group (14.29%) compared with the A group (37.21%)was significantly lower (P<0.05). The survival and recurrence rates between the two groups has no significant difference (P>0.05). Conclusion Laparoscopic surgery can significantly improve the clinical indicators, serum inflammatory factors, and immune molecular levels in elderly patients with colon cancer, and reduce the complications of patients, and there is no significant difference between the survival rate and recurrence rate and open surgery. |