| 刘永收,胡鹏刚,张昌明,李丹凤,丁忠佳,石 力,查定军.改良悬雍垂腭咽成形术联合鼻腔扩容手术对OSAHS患者睡眠质量、认知功能及生活质量的影响[J].,2020,(24):4623-4626 |
| 改良悬雍垂腭咽成形术联合鼻腔扩容手术对OSAHS患者睡眠质量、认知功能及生活质量的影响 |
| Effects of Modified Uvulopalatopharyngoplasty Combined with Nasal Dilatation on Sleep Quality, Cognitive Function and Quality of Life in Patients with OSAHS |
| 投稿时间：2020-06-26 修订日期：2020-07-22 |
| DOI：10.13241/j.cnki.pmb.2020.24.005 |
| 中文关键词: 改良悬雍垂腭咽成形术 睡眠质量 阻塞性睡眠呼吸暂停低通气综合征 认知功能 生活质量 鼻腔扩容手术 |
| 英文关键词: Modified uvulopalatopharyngoplasty Sleep quality Obstructive sleep apnea hypopnea syndrome Cognitive function Quality of life Nasal dilatation |
| 基金项目:国家重点研发计划项目（2019YBF1311605）；西京医院学科助推项目（XJZT18MDT07） |
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| 中文摘要: |
| 摘要 目的：探讨改良悬雍垂腭咽成形术（UPPP）联合鼻腔扩容手术对阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者认知功能、睡眠质量及生活质量的影响。方法：回顾性分析2015年7月~2019年12月期间我院收治的115例OSAHS患者的临床资料，根据手术方式的不同分为A组（n=56，UPPP）和B组（n=59，UPPP联合鼻腔扩容手术），比较两组患者疗效、睡眠质量、认知功能、生活质量及并发症发生率。结果：B组治疗2个月后的临床总有效率高于A组（P<0.05）。两组术后2个月匹兹堡睡眠质量指数（PSQI）评分、呼吸暂停低通气指数（AHI）、Epworth嗜睡量表（ESS）评分均较术前降低，且B组低于A组（P<0.05）。两组术后2个月社会功能、健康状况、躯体疼痛、生理职能、精神健康、生理机能、活力、情感职能维度评分均较术前升高，且B组高于A组（P<0.05）。两组术后2个月简易智力状态量表（MMSE）评分均较术前升高，且B组高于A组（P<0.05）。两组术后并发症发生率比较差异无统计学意义（P>0.05）。结论：UPPP联合鼻腔扩容手术治疗OSAHS患者，疗效确切，可有效改善患者睡眠质量及生活质量，改善患者认知功能，且不增加并发症发生率。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effect of modified uvulopalatopharyngoplasty（UPPP）combined with nasal dilatation on sleep quality, cognitive function and quality of life in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). Methods: The clinical data of 115 OSAHS patients in our hospital from July 2015 to December 2019 were retrospectively selected. They were divided into group A (n=56, UPPP) and group B (n=59, UPPP combined with nasal dilatation) according to the different operation methods, the clinical efficacy, sleep quality, cognitive function, quality of life and the incidence of complications in the patients were compared between the two groups. Results: The total clinical effective rate of group B was higher than that of group A after 2 months treatment (P<0.05). The scores of pittsburgh sleep quality index （PSQI）, apnea hypopnea index（AHI） and epworth sleepiness scale (ESS) in two groups were lower than those before operation, 2 months after operation (P<0.05). the scores of social function, health status, physical pain, physiological function, mental health, physiological function, vitality, emotional function and other dimensions in the two groups were higher than those before operation 2 months after operation, and the group B were higher than those in group A (P<0.05). The score of mini-mental state examination（MMSE）in the two groups was lower than that before operation 2 months after operation, and the group B was higher than that in group A (P<0.05). There was no significant difference in the incidence of postoperative complications between the two groups (P>0.05). Conclusion: The modified uvulopalatopharyngoplasty combined with nasal dilatation can effectively improve the quality of sleep and life of OSAHS patients, reduce cognitive impairment, and do not increase the incidence of complications. |
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