| 唐雪彬,谢 林,李 华,王云清,房明亮.PVP治疗新鲜期OVCF伴随和不伴随椎体内裂隙征疗效比较[J].,2020,(23):4450-4454 |
| PVP治疗新鲜期OVCF伴随和不伴随椎体内裂隙征疗效比较 |
| Comparison of Effect of PVP on OVCF in Fresh Stage with or without Intravertebral Cleft |
| 投稿时间：2020-05-23 修订日期：2020-06-17 |
| DOI：10.13241/j.cnki.pmb.2020.23.011 |
| 中文关键词: OVCF PVP 椎体内裂隙征 新鲜期 疗效 |
| 英文关键词: OVCF PVP Intravertebral Cleft Fresh period Curative effect |
| 基金项目:江苏省社会发展重点项目（BE2019765） |
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| 中文摘要: |
| 摘要 目的：对经皮椎体成形术(percutaneous vertebroplasty，PVP)治疗新鲜期（急性期和亚急性期）骨质疏松性椎体压缩性骨折(osteoporotic vertebral compression fracture，OVCF)伴随和不伴随椎体内裂隙征疗效进行比较。方法：以行PVP术治疗OVCF的患者为研究对象，其中研究组A为OVCF伴随椎体内裂隙征(intravertebral cleft, IVC)患者，研究组B为OVCF不伴随IVC患者，以手术时间、所使用的骨水泥量，手术前、术后2 d、术后6个月患者VAS评分、骨折椎体前缘高度及Cobb角为指标，考察PVP的治疗效果。结果：与研究组A比较，研究组B急性期和亚急性期患者手术时间均无显著差异（P＞0.05），研究组B骨水泥量显著降低（P＜0.05）。两组急性期和亚急性期患者手术前、术后2 d和6个月的VAS评分均无显著差异（P＞0.05）；同组急性和亚急性期患者手术前后VAS评分无显著差异（P＞0.05）；与手术前相比，两组患者术后2 d和6个月的VAS评分显著降低（P＜0.05）。两组急性期和亚急性期患者骨折椎体前缘高度无显著差异（P＞0.05）；与同组急性期比较，术前亚急性期患者骨折椎体前缘高度显著降低（P＜0.05）；与手术前比较，术后2 d和术后6个月骨折椎体前缘高度均显著增加（P＜0.05），术后A组急性期和亚急性期患者椎体前缘高度较术后B组显著增加（P＜0.05）。术前B组急性期和亚急性期患者Cobb角较A组无显著差异（P＞0.05），与同组急性期比较，术前亚急性期患者Cobb角显著升高（P＜0.05）；与手术前比较，两组术后2 d和术后6个月的Cobb角均显著降低（P＜0.05），术后A组急性期和亚急性期患者Cobb度显著低于术后B组（P＜0.05）。结论：PVP治疗新鲜期OVCF伴随和不伴随椎体内裂隙征均有较好的疗效。 |
| 英文摘要: |
| ABSTRACT Objective: To compare the efficacy of OVCF(osteoporotic vertebral compression fracture) with or without intravertebral cleft in the fresh phase of PVP(percutaneous vertebroplasty) treatment (acute phase and subacute phase). Methods: Patients with OVCF treated with PVP were taken as the research subjects. Among them, study group A was OVCF patients with IVC(intravertebral cleft, IVC), and study group B was OVCF patients without IVC. The operation time, bone cement volume, VAS score, anterior edge height of fractured vertebra and Cobb angle were used as indicators to evaluate the therapeutic effect of PVP. Results: There was no significant difference in the operation time in the acute and non-acute phases between study group A and study group B (P>0.05), and the amount of bone cement in study group B was significantly reduced (P<0.05). There was no significant difference in the VAS scores before operation, 2 d after operation, and 6 months after operation between the two groups of patients in the acute and subacute phases (P>0.05). There was no significant difference in the VAS scores before and after surgery of the patients in the acute and non-acute phases of the same group (P>0.05); compared with before surgery, the VAS scores of the two groups of patients were significantly lower 2 d and 6 months after surgery (P<0.05). There was no significant difference in the height of the front edge of the fractured vertebral body between the two groups of patients in the acute and subacute phases (P>0.05), compared with the acute phase of the same group, the height of the front edge of the fractured vertebral body in the subacute phase before surgery was significantly reduced (P<0.05). Compared with before operation, the height of the anterior edge of the fractured vertebral body increased significantly at 2 days and 6 months after the operation (P<0.05). The height of the anterior edge of the vertebral body in the acute and subacute phases of group A increased significantly compared with group B (P<0.05). There was no significant difference in the Cobb angle between the acute and subacute patients in group B before the operation (P>0.05). Compared with the same group in the acute phase, the Cobb angle of the patients in the subacute phase before the operation was significantly increased (P<0.05); and before the operation, the Cobb angles of the two groups were significantly reduced 2 days after the operation and 6 months after the operation (P<0.05). The Cobb degree of the acute and subacute patients in group A was significantly lower than that in group B after operation (P＜0.05). Conclusion: PVP has a good effect on fresh OVCF with and without IVC. |
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