| 张荣繁,于 芹,庞 鑫,周 源,牛丽红.图像引导下精确放疗治疗宫颈癌的价值分析[J].,2020,(19):3732-3735 |
| 图像引导下精确放疗治疗宫颈癌的价值分析 |
| Value Analysis of Image-guided Precise Radiotherapy for Cervical Cancer |
| 投稿时间：2019-12-30 修订日期：2020-01-27 |
| DOI：10.13241/j.cnki.pmb.2020.19.028 |
| 中文关键词: 图像引导 精确放疗 宫颈癌 免疫功能 毒副反应 |
| 英文关键词: Image-guided Precise radiotherapy Cervical cancer Immune function Toxic side effects |
| 基金项目:内蒙古自治区自然科学基金项目（YKD2017KJ ） |
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| 中文摘要: |
| 摘要 目的：探讨与分析图像引导下精确放疗治疗宫颈癌的价值。方法：2016年1月至2017年12月选择在本院进行诊治的宫颈癌患者120例，根据治疗方法的不同把患者分为观察组80例与对照组40例。对照组给予常规放疗方法，观察组给予图像引导下精确放疗，记录与随访两组的预后情况。结果：治疗后观察组的总有效率为85.0 %，显著高于对照组的60.0%(P<0.05)。观察组治疗期间的放射性直肠损伤、放射性膀胱损伤、消化道反应、血液系统反应等毒副反应发生率显著低于对照组(P<0.05)。观察组治疗后的IgG与IgA值都显著高于治疗前(P<0.05)，也高于对照组(P<0.05)，对照组治疗前后对比差异无统计学意义(P>0.05)。Kapplan-meier法分析显示观察组的无疾病进展生存时间和总生存时间都显著长于对照组(P<0.05)。结论：图像引导下精确放疗治疗宫颈癌能促进患者免疫功能的恢复，提高治疗效果与减少毒副反应的发生，从而延长患者的生存时间。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate and analyze the value of image-guided precise radiotherapy for cervical cancer. Methods: From January 2016 to December 2017, 120 patients with cervical cancer who were treated in our hospital were selected and were divided into the observation group (n=80) and control group (n=40) accorded to different treatment methods. The control group were given conventional radiotherapy, and the observation group were given image-guided precise radiotherapy. The prognosis of the two groups were recorded and followed up. Results: The total effective rates of the observation group after treatment were 85.0%, which were significantly higher than that of the control group (60.0%)(P<0.05). The incidence of toxic side effects such as radiation rectal injury, radiation bladder injury, digestive tract reaction and blood system reaction during the treatment in the observation group were significantly lower than that of the control group(P<0.05). The IgG and IgA values in the observation group after treatment were significantly higher than those before treatment(P<0.05), and were also higher than the control group(P<0.05), and there were no significant difference in the the control group compared before and after the treatment(P>0.05). Kapplan-meier analysis showed that the disease-free survival time and overall survival time of the observation group were significantly longer than the control group(P<0.05). Conclusion: Image-guided precise radiotherapy for cervical cancer can promote the recovery of immune function, improve the treatment effect and reduce the occurrence of toxic and side effects, thus prolonging the survival time of patients. |
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