| 汪 亮,贺崇欣,曹光东,饶 晖,杜 进,徐善水,张 扬.血管内介入栓塞术治疗脑动脉瘤的疗效及对生活质量和预后的影响[J].,2020,(18):3519-3523 |
| 血管内介入栓塞术治疗脑动脉瘤的疗效及对生活质量和预后的影响 |
| Effect of Endovascular Embolization on Quality of Life and Prognosis of Cerebral Aneurysms |
| 投稿时间：2019-12-30 修订日期：2020-01-25 |
| DOI：10.13241/j.cnki.pmb.2020.18.027 |
| 中文关键词: 血管内介入栓塞术 脑动脉瘤 疗效 生活质量 预后 |
| 英文关键词: Endovascular embolization Cerebral aneurysm Efficacy Quality of life Prognosis |
| 基金项目:安徽省卫生计生委医学科研基金项目（17ZC349） |
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| 中文摘要: |
| 摘要 目的：探讨血管内介入栓塞术治疗脑动脉瘤的疗效及对生活质量和预后的影响。方法：回顾性分析我院于2014年1月~2019年3月期间收治的80例脑动脉瘤患者的临床资料，根据手术方式的不同分为A组（n=38，开颅夹闭术）和B组（n=42，血管内介入栓塞术），比较两组患者临床疗效、生活质量、预后、复发率、并发症发生率及围术期指标。结果：B组术后6个月的临床总有效率为85.71%（36/42），高于对照组的65.79%（25/38）（P<0.05）。两组患者术后6个月躯体功能、社会功能、认知功能、情绪功能、角色功能评分均升高，且B组高于A组（P<0.05）。两组轻度残障率、重度残障率、植物生存率、死亡率以及复发率比较差异无统计学意义（P>0.05）；B组预后良好率明显高于A组（P<0.05）。两组并发症发生率比较无差异（P>0.05）。B组手术时间、住院天数、切口长度均短于A组，但住院费用高于A组（P<0.05）。结论：与开颅夹闭术相比，血管内介入栓塞术治疗脑动脉瘤，疗效确切，可有效改善患者生活质量及预后，且不增加复发率及并发症发生率，临床应用价值较高。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effect of endovascular embolization on the quality of life and prognosis of cerebral aneurysms. Methods: The clinical data of 80 patients with cerebral aneurysms who were admitted to our hospital from January 2014 to March 2019 were retrospectively analyzed. The patients were divided into group A (n=38, craniotomy clipping) and group B (n=42, endovascular embolization) according to the different surgical methods. The clinical efficacy, quality of life, prognosis, recurrence rate, incidence of complications and perioperative indicators were compared between the two groups. Results: The total effective rate of group B was 85.71% (36/42) at 6 months after operation, which was higher than 65.79% (25/38) of the control group (P<0.05). The scores of somatic function, social function, cognitive function, emotional function and role function were increased between two groups at 6 months after operation, and those of group B were higher than those of group A (P<0.05). There was no significant difference in mild disability, severe disability, plant survival, mortality and recurrence rate between the two groups (P>0.05). The good prognosis rate of group B was significantly higher than that of group A (P<0.05). There was no significant difference in the incidence of complications between two groups during the follow-up period (P>0.05). The operation time, hospitalization days and incision length of group B were shorter than those pf group A, but the hospitalization expenses were higher than those of group A (P<0.05). Conclusion: Compared with craniotomy, endovascular embolization for cerebral aneurysms has definite curative effect, it can effectively improve the quality of life and prognosis of patients, and it does not increase the recurrence rate and the incidence of complications. It has high clinical value. |
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