| 陈思攀,张京京,董永安,张 矛,贺荣荣.子宫动脉化疗栓塞与单子宫动脉栓塞在瘢痕妊娠治疗有效性对比[J].,2020,(17):3274-3277 |
| 子宫动脉化疗栓塞与单子宫动脉栓塞在瘢痕妊娠治疗有效性对比 |
| Comparison of the Effectiveness of Uterine Artery Chemoembolization and Single Uterine Artery Embolization in the Treatment of Scar Pregnancy |
| 投稿时间：2020-01-07 修订日期：2020-01-31 |
| DOI：10.13241/j.cnki.pmb.2020.17.016 |
| 中文关键词: 子宫动脉化疗栓塞 单子宫动脉栓塞 瘢痕妊娠 卵巢功能 |
| 英文关键词: Uterine arterial chemoembolization Single uterine arterial embolization Scar pregnancy Ovarian function |
| 基金项目:陕西省重点研发计划项目（2018SF-169） |
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| 中文摘要: |
| 摘要 目的：对比子宫动脉化疗栓塞与单子宫动脉栓塞在瘢痕妊娠治疗中的有效性。方法：选择2016年1月-2018年12月在我院诊治的瘢痕妊娠患者96例，根据手术方式不同分为两组，各48例，其中，对照组采用单子宫动脉栓塞治疗，研究组采用子宫动脉化疗栓塞治疗，记录并对比两组术中出血量、手术时间、住院时间、人绒毛膜促性腺激素β亚单位（human chorionic gonadotrop(h)in-beta subunit，β-HCG）下降至正常范围时间、宫腔异常包块消失时间、月经恢复正常时间、首次肛门排气时间等指标；记录并对比两组患者治疗前后的卵泡刺激素（follicle stimulating hormone，FSH）、黄体生成素（luteinizing hormone，LH）、雌二醇（estradiol，E2）、抑制素B（inhibin B，INHB）等卵巢功能指标变化；记录并对比两组的膀胱损伤、阴道流血、感染等术后并发症的发生情况。结果：研究组的术中出血量、手术时间、住院时间均显著少于（短于）对照组（P＜0.05）；研究组的β-HCG下降至正常范围时间、宫腔异常包块消失时间、月经恢复正常时间、首次肛门排气时间均显著短于对照组（P＜0.05）；治疗前，两组的FSH、LH、E2、INHB等卵巢功能指标对比均无显著性差异（P＞0.05）；治疗后，两组的FSH水平均升高，LH、E2、INHB水平均降低，且研究组更优（P＜0.05）；研究组的并发症发生率显著低于对照组（6.25 % vs. 20.83 %，P＜0.05）。结论：相比于单子宫动脉栓塞，子宫动脉化疗栓塞有利于改善瘢痕妊娠患者的手术相关指标及术后恢复情况，对患者卵巢功能的恢复较好，且安全性较高，值得推荐至临床广泛应用。 |
| 英文摘要: |
| ABSTRACT Objective: To compare the effectiveness of uterine artery chemoembolization and single uterine artery embolization in the treatment of scar pregnancy. Methods: A total of 96 patients with scar pregnancy diagnosed and treated in our hospital from January 2016 to December 2018 were selected as study subjects. According to the different surgical methods, they were divided into two groups, with 48 patients. Among them, patients in the control group were treated with single uterine artery embolization, and patients in the study group were treated with uterine artery chemoembolization.ecord and compare the intraoperative bleeding volume, operation time, length of hospital stay, time for β-HCG to fall to normal range, time for abnormal mass loss of uterine cavity, time for menstrual recovery to normal, time for first anal exhaust.Changes in ovarian function indexes such as FSH, LH, E2, INHB before and after treatment were recorded and compared between the two groups of patients; postoperative complications such as bladder injury, vaginal bleeding, and infection were recorded and compared between the two groups. Results: The intraoperative blood loss, operation time, and hospital stay of the study group were significantly less (shorter) than those of the control group(P<0.05). The time of β-HCG decline to normal range, the time of disappearance of abnormal uterine mass, the time of normal menstruation, and the time of first anal exhaust were significantly shorter in the study group than in the control group(P<0.05). Pretherapy, there was no significant difference in FSH, LH, E2, INHB and other ovarian function indicators between the two groups of patients(P>0.05). Post-treatment, the levels of FSH in the two groups increased, and the levels of LH, E2, and INHB decreased, and the study group was better (P<0.05). The incidence of complications in the study group was ignificantly lower than that in the control group(6.25 % vs. 20.83 %, P<0.05). Conclusion: Compared with single uterine arterial embolization, uterine arterial chemoembolization is beneficial to improve the surgical related indexes and postoperative recovery of patients with scar pregnancy. |
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