| 李 梅,汪小五,刘 艳,吴 亚,高 勇.新型冠状病毒肺炎患者血清SAA、ESR、CRP检测结果分析[J].,2020,(10):1949-1951 |
| 新型冠状病毒肺炎患者血清SAA、ESR、CRP检测结果分析 |
| Analysis of Serum Amyloid A, Serum Sedimentation and C-reactive Protein in COVID-19 Patients |
| 投稿时间：2020-03-30 修订日期：2020-04-23 |
| DOI：10.13241/j.cnki.pmb.2020.10.033 |
| 中文关键词: ESR CRP SAA COVID-19 |
| 英文关键词: Erythrocyte sedimentation rate C-reactive protein Serum amylase A COVID-19 |
| 基金项目:江苏省自然科学基金项目(2016C256) |
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| 中文摘要: |
| 摘要 目的：分析新型冠状病毒肺炎（COVID-19）患者血清淀粉样蛋白A（SAA）、血沉ESR（ESR）、C-反应蛋白CRP（CRP）的临床价值。方法：以我院2020年1月至2020年2月确诊的COVID-19患者51例为实验组：其中重症患者21例，轻症患者30例，选取非感染患者30例为对照组。分析新型冠状病毒肺炎（COVID-19）患者血清SAA、ESR、CRP水平以及临床价值。结果：实验组SAA、ESR、CRP水平高于对照组（P＜0.05）；重症组SAA、ESR、CRP水平高于轻症组（P＜0.05），由ROC曲线得知SAA、ESR、CRP预测COVID-19的AUC小于三者联合预测的AUC。结论：COVID-19的SAA、ESR、CRP水平会升高，三者联合预测为疾病评估、预测疾病发展的提供依据，值得临床进一步推广应用。 |
| 英文摘要: |
| ABSTRACT Objective: To analyze of the clinical values of serum amyloid A (SAA), serum sedimentation (ESR) and c-reactive protein (CRP) in sera from COVID-19 patients. Methods: 51 patients with COVID-19 diagnosed in our hospital from January 2020 to February 2020 were involved as the experimental group. Among them, 21 severe patients, 30 mild patients, and 30 non-infected patients were treated as the control group. The levels of SAA, ESR and CRP were detected sera from COVID-19 patients. Results: The levels of SAA, ESR and CRP in the experimental group were higher than those in the control group (P<0.05).The levels of SAA, ESR and CRP in the severe group were higher than that in the mild group (P<0.05). According to the ROC curve, the AUC of SAA, ESR and CRP in the prediction of COVID-19 was lower than that in the combined detection of the three. Conclusion: The serum levels of SAA, ESR and CRP of COVID-19 will increase. The Combined detection of SAA, ESR and CRP can improve the accuracy of diagnosis of COVID-19. It provides the basis for clinical prediction and treatment to evaluate the disease and predict the development of the disease. |
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