| 王丹丹,朱丽颖,孙琪瑛,朱永娟,许周美.剖宫产术围术期预防性应用抗生素的成本效果分析[J].,2020,(5):893-896 |
| 剖宫产术围术期预防性应用抗生素的成本效果分析 |
| Cost-effectiveness Analysis of Prophylactic Use of Antibiotics during Perioperative Period of Cesarean Section |
| 投稿时间：2019-07-26 修订日期：2019-08-21 |
| DOI：10.13241/j.cnki.pmb.2020.05.020 |
| 中文关键词: 剖宫产术 围术期 预防性抗生素 成本效果 |
| 英文关键词: Cesarean section Perioperative period Preventive antibiotics Cost-effectiveness |
| 基金项目:上海市卫生计划生育委员会基金项目(20144y0111) |
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| 中文摘要: |
| 摘要 目的：探讨剖宫产术围术期预防性应用抗生素的成本效果，为剖宫产手术提供有效、经济的抗生素应用方案。方法：选取我院近3年接诊的80例实施剖宫产产妇纳入本次研究，将其随机分为研究组和对照组，每组产妇40例。研究组在胎儿娩出断脐后立即静脉滴注头孢呋辛，术后不再应用抗生素，而对照组术后静脉滴注头孢呋辛，对比两组产妇的成本效果。结果：两组产妇术后体温(平均体温、最高体温)、体温恢复时间、住院时间和术后感染发生率对比均无统计学差异(P＞0.05)；研究组成本效果明显低于对照组(P＜0.05)。结论：剖宫产术围术期预防性应用抗生素可达到良好的抗感染效果，选择头孢呋辛作为剖宫产手术围术期预防性抗菌药物，是一种有效、经济的方案，可避免围术期过度使用抗生素。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the cost-effectiveness of prophylactic antibiotic use in perioperative period of cesarean section, to provide effective and economical antibiotic application program for cesarean section. Methods: 80 cases of parturients who received cesarean section in our hospital in recent three years were selected and randomly divided into study group and control group, 40 cases in each group. In study group, cefuroxime was intravenously dripped immediately after the delivery of the umbilical cord, and no antibiotics were used after the operation. In control group, cefuroxime was intravenously dripped after the operation, cost-effectiveness were compared between the two groups. Results: There was no significant difference between the two groups in body temperature (average body temperature, maximum body temperature), recovery time of body temperature, hospitalization time and incidence of postoperative infection (P>0.05); The cost and effect of the study group was significantly lower than that of the control group (P<0.05). Conclusion: Preventive use of antibiotics during the perioperative period of cesarean section can achieve good anti-infective effect. Choosing cefuroxime as a preventive antibiotic during the perioperative period of cesarean section is an effective and economical scheme, and excessive perioperative antibiotic use can be avoided. |
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