文章摘要
冯钟煦,顾家琪,刘 剑,李 丹,高建伟,张惠杰,戴冬秋.普外科患者术后切口感染病原菌分布情况及影响因素logistic回归分析[J].,2019,19(23):4553-4557
普外科患者术后切口感染病原菌分布情况及影响因素logistic回归分析
Logistic Regression Analysis of Pathogen Distribution and Influencing Factors of Postoperative Incision Infection in General Surgery Patients
投稿时间:2019-06-06  修订日期:2019-06-30
DOI:10.13241/j.cnki.pmb.2019.23.036
中文关键词: 普外科  切口感染  病原菌  影响因素
英文关键词: General surgery  Incision infection  Pathogenic bacteria  Influencing factors
基金项目:河北省科学技术厅科技支撑项目(20161621)
作者单位E-mail
冯钟煦 河北省秦皇岛市第一医院普通外科一病区 河北 秦皇岛 066000 pw1kgujiaqi@126.com 
顾家琪 河北省秦皇岛市第一医院普通外科一病区 河北 秦皇岛 066000  
刘 剑 河北省秦皇岛市第一医院普通外科一病区 河北 秦皇岛 066000  
李 丹 河北省秦皇岛市第一医院普通外科一病区 河北 秦皇岛 066000  
高建伟 河北省秦皇岛市第一医院普通外科一病区 河北 秦皇岛 066000  
张惠杰 河北省秦皇岛市第一医院检验科 河北 秦皇岛 066000  
戴冬秋 中国医科大学附属第四医院胃肠外科 辽宁 沈阳 110000  
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中文摘要:
      摘要 目的:探讨普外科患者术后切口感染的病原菌分布情况及影响因素。方法:回顾性分析2017年9月-2019年1月河北省秦皇岛市第一医院普通外科一病区接受手术治疗的150例患者的临床资料,术后发生切口感染的75例患者作为感染组,术后未发生切口感染的75例患者作为对照组,分析术后切口感染的病原菌分布情况,并比较两组患者的临床资料,对普外科患者术后切口感染的影响因素进行多因素Logistic回归分析。结果:感染组分离出病原菌75株,包括43株革兰阴性菌(57.33%)、28株革兰阳性菌(27.33%)、4株真菌(5.33%),经单因素分析显示,年龄、手术时间、有无合并糖尿病、有无植入性器械、住院时间与普外科患者术后切口感染有关(P<0.05);经多因素Logistic分析显示,年龄≥60岁、合并糖尿病、手术时间≥2 h、有植入性器械、住院时间≥1月为普外科患者术后切口感染的独立危险因素(P<0.05)。结论:普外科患者术后切口感染病原菌株以革兰阴性菌和革兰阳性菌为主,针对术后切口感染的危险因素实施干预措施,可以降低术后切口感染率,保证患者手术效果和改善预后。
英文摘要:
      ABSTRACT Objective: To investigate the distribution and influencing factors of pathogens in postoperative incision infection in general surgery patients. Methods: A retrospective analysis was made of the clinical data of 150 patients treated by general surgery in First Ward of Department of General Surgery, Qinhuangdao First Hospital of Hebei Province. 75 patients with incision infection after operation were treated as infection group, and 75 patients without incision infection after operation were treated as control group. The distribution of pathogenic bacteria in postoperative incision infection was analyzed, and the clinical data of the two groups were compared. The influencing factors of postoperative incision infection in general surgery patients were analyzed by multivariate logistic regression analysis. Results: The 75 strains of pathogenic bacteria were isolated from the incision infection, including 43 Gram-negative bacteria (57.33%), 28 Gram-positive bacteria (27.33%), and 4 fungi (5.33%). Univariate analysis showed that age, operative time, with or without diabetes mellitus, with or without implantable instruments, and hospitalization time were independent risk factors for postoperative incision infection in general surgery patients (P<0.05). Multivariate logistic analysis showed that age ≥60 years old, with diabetes mellitus, operation time≥2 h, with implantable instruments and hospitalization time≥11 month were independent risk factors for incision infection after general surgery (P<0.05). Conclusion: The pathogens of postoperative incision infection in general surgery patients are mainly Gram-positive bacteria and Gram-negative bacteria, and impleme interventions for risk factors for postoperative incision infection can reduce the postoperative incision infection rate, it can ensure the patient's surgical effect and improve the prognosis.
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