文章摘要
王晓庆,贺京军,周建群,韦怡芸,刘川深.健康体检人员脂肪肝超声诊断结果及其危险因素分析[J].,2019,19(19):3716-3719
健康体检人员脂肪肝超声诊断结果及其危险因素分析
Ultrasound Diagnosis of Fatty Liver and Analysis of Risk Factors Among Health Check-up Personnel
投稿时间:2019-03-05  修订日期:2019-03-28
DOI:10.13241/j.cnki.pmb.2019.19.027
中文关键词: 脂肪肝  超声  诊断  健康检查  危险因素
英文关键词: Fatty liver  Ultrasound  Diagnosis  Health check-up  Risk factors
基金项目:广东省医学科研基金资助项目(A201701109)
作者单位E-mail
王晓庆 广东省第二人民医院体检科 广东 广州 510317 miss_wang86@sina.com 
贺京军 广东省第二人民医院体检科 广东 广州 510317  
周建群 广东省第二人民医院体检科 广东 广州 510317  
韦怡芸 广东省第二人民医院体检科 广东 广州 510317  
刘川深 广东省第二人民医院体检科 广东 广州 510317  
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中文摘要:
      摘要 目的:了解健康体检人员脂肪肝超声诊断结果,分析患病危险因素。方法:选择2018年2月至2018年8月我院体检科接受体检的人员1078例,应用超声对脂肪肝进行筛查,统计受检者脂肪肝超声诊断结果,分析脂肪肝发病的性别、年龄分布情况,应用单因素和多因素Logistic回归分析脂肪肝发病的临床相关因素。结果:1078例受检者中发现脂肪肝158例,占14.66%,其中女性43例,检出率为9.31%,男性115例,检出率为18.67%,男性脂肪肝检出率显著高于女性(P<0.05)。男性受检者和女性受检者46~55岁年龄段检出率最高,不同年龄段男性、女性受检者脂肪肝检出率均有统计学差异(P<0.05)。多因素Logistic回归分析显示:饮酒、体质指数(BMI)≥28 kg/m2、糖尿病、胆石症、总胆固醇(TC)升高、总甘油三酯(TG)升高、低密度脂蛋白胆固醇(LDL-C)升高、谷草转氨酶(ALT)和(或)谷丙转氨酶(AST)升高均为脂肪肝发病的独立危险因素(P<0.05)。结论:我院健康体检人员脂肪肝检出率为14.66%,男性脂肪肝检出率显著高于女性,且46~55岁年龄段检出率最高。饮酒、BMI≥28 kg/m2、糖尿病、胆石症、TC升高、TG升高、LDL-C升高、ALT和(或)AST升高均为脂肪肝发病的独立危险因素,值得临床重点关注。
英文摘要:
      ABSTRACT Objective: To understand the results of ultrasound diagnosis of fatty liver among health check-up personnel, and to analyze the risk factors of fatty liver disease. Methods: 1078 cases of fatty liver who were selected from February 2018 to August 2018 in the physical examination department of our hospital. Ultrasound was used to screen fatty liver. The diagnostic results of fatty liver were gathered statistics. The sex and age distribution of fatty liver were analyzed. The clinical related factors of fatty liver were analyzed by single factor and multi-factor logistic regression analysis. Results: 158 cases of 1078 patients were found to have fatty liver, accounted for 14.66%. Among them, 43 cases were female, the detection rate was 9.31%, 115 cases were male, the detection rate was 18.67%. The detection rate of male fatty liver was significantly higher than that of female(P<0.05). The detection rate of fatty liver was the highest in male and female patients aged 46-55 years, and there were significant differences in the detection rate of fatty liver between male and female patients of different ages(P<0.05). Multivariate logistic regression analysis showed that alcohol consumption, body mass index (BMI) ≥28 kg/m2, diabetes mellitus, cholelithiasis, elevated total cholesterol (TC), elevated total triglyceride (TG), elevated low density lipoprotein cholesterol (LDL-C), elevated glutathione transaminase (ALT) and/or alanine aminotransferase (AST) were independent risk factors for fatty liver(P<0.05). Conclusion: The detection rate of fatty liver is 14.66% in the health examination personnel of our Hospital. The detection rate of male fatty liver is significantly higher than that of female, and the detection rate is the highest in the age group of 46-55 years. Alcohol consumption, BMI≥28 kg/m2, diabetes mellitus, cholelithiasis, elevated TC, elevated TG, elevated LDL-C, elevated ALT and/or AST are all independent risk factors for fatty liver, which deserve clinical attention.
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