| 赵大委,陈 如,马 锋,周 俊,李升平.经尿道针状电极膀胱肿瘤整块切除术治疗膀胱癌的临床分析[J].,2019,19(11):2197-2200 |
| 经尿道针状电极膀胱肿瘤整块切除术治疗膀胱癌的临床分析 |
| Curative Efficacy of Transurethral Needle Electrode Excision for Bladder Tumor in the Treatment of Bladder Cancer |
| 投稿时间：2019-02-12 修订日期：2019-03-04 |
| DOI：10.13241/j.cnki.pmb.2019.11.043 |
| 中文关键词: 尿道针状电极膀胱肿瘤整块切除术 膀胱癌 疗效 生活质量 |
| 英文关键词: Urethral needle electrode lumpectomy for bladder tumor Bladder cancer Curative effect The quality of life |
| 基金项目:陕西省自然科学基础研究计划项目(2015JQ8308) |
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| 中文摘要: |
| 摘要 目的：探讨经尿道针状电极膀胱肿瘤整块切除术治疗膀胱癌的临床疗效及安全性。方法：选择2015年1月-2017年1月我院收治的膀胱癌患者100例纳入本次研究，根据简单随机分组法分为观察组(n=51)和对照组(n=49)。对照组使用尿道膀胱肿瘤电切术治疗，观察组采用经尿道针状电极膀胱肿瘤整块切除术进行治疗。比较两组患者临床疗效、手术情况、治疗前后生活质量的变化及并发症的发生情况和复发率。结果：治疗后，两组患者的临床总有效率分别为82.35%、61.22%，观察组显著高于对照组(P＜0.05)；两组患者手术时间比较无显著性差异(P>0.05)；观察组患者尿管留置时间、术中出血量及住院时间均显著低于对照组(P＜0.05)；两组患者治疗后生活质量评分均较治疗前显著提高，且观察组显著高于对照组(P＜0.05)；两组患者并发症总发生率分别为1.96%、24.49%，复发率分别为9.8%、34.69%，观察组均显著低于对照组(P＜0.05)。结论：采用经尿道针状电极膀胱肿瘤整块切除术治疗膀胱癌的临床疗效显著优于尿道膀胱肿瘤电切术治疗，其可有效改善患者的生活质量，且安全性更高。 |
| 英文摘要: |
| ABSTRACT Objective: To study Curative efficacy of Transurethral needle electrode excision for bladder tumor in treatment of Bladder cancer. Methods: 100 cases of bladder cancer patients admitted to our hospital from January 2015 to January 2017 were selected for this study, the patients were divided into observation group (n=51) and control group (n=49) by simple random grouping. The control group was treated with urethrocystectomy, and the observation group was treated with transurethral needle electrode complete cystectomy. The clinical efficacy, surgical conditions, changes in quality of life before and after treatment, complications and recurrence rates were compared between the two groups. Results: After treatment, the total clinical effective rates of the two groups were 82.35% and 61.22%, respectively. The observation group was significantly higher than the control group (P<0.05). There was no significant difference in operation time between the two groups (P>0.05). The indwelling time, intraoperative blood loss and hospitalization time of the observation group were significantly lower than those of the control group (P<0.05). Quality of life scores of patients in the two groups after treatment were significantly improved compared with that before treatment, and the observation group was significantly higher than the control group (P<0.05). The total incidence of complications in the two groups were 1.96%, 24.49%, 9.8% and 34.69%, respectively. The observation group was significantly lower than the control group (P<0.05). Conclusion: The clinical efficacy of transurethral needle electrode complete cystectomy for bladder cancer is significantly better than that of urethrocystectomy, which can effectively improve the quality of life of patients with higher safety. |
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