| 闫崇超,曹 硕,金 浩,张 娜,郝建学.后路内固定融合术对胸腰段脊柱骨折患者椎体参数与创伤应激状态的影响研究[J].,2019,19(8):1526-1528 |
| 后路内固定融合术对胸腰段脊柱骨折患者椎体参数与创伤应激状态的影响研究 |
| A Study on the Influence of Posterior Internal Fixation and Fusion on the Vertebral Body Parameters and Trauma Stress State of Patients with Thoracolumbar Spine Fracture |
| 投稿时间：2018-10-10 修订日期：2018-10-31 |
| DOI：10.13241/j.cnki.pmb.2019.08.028 |
| 中文关键词: 后路内固定融合术 胸腰段脊柱骨折 椎体参数 创伤应激状态 |
| 英文关键词: Posterior internal fixation and fusion Thoracolumbar spine fracture Vertebral body parameters Trauma stress state |
| 基金项目:国家自然科学基金青年基金项目( 30901795) |
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| 中文摘要: |
| 摘要 目的：探究后路内固定融合术对胸腰段脊柱骨折患者椎体参数与创伤应激状态的影响。方法：选取2016年11月~2017年11月我院收治的60例胸腰段脊柱骨折患者为研究对象，将其依据治疗方式的不同分为对照组(前路内固定融合术组)30例和观察组(后路内固定融合术组)30例。比较两组手术前后的椎体参数与血清促肾上腺皮质激素(ACTH)、皮质醇(Cor)及肿瘤坏死因子α(TNF-α)水平的变化。结果：术后1个月及6个月，两组的Cobb角均较术前减小，椎体前、后缘高度均较术前增加，且观察组Cobb角均低于对照组，而椎体前、后缘高度均高于对照组。术后1周，两组血清ACTH、Cor水平升高，观察组以上指标明显低于对照组(P＜0.05)，观察组TNF-α水平较术前明显下降，而对照组较术前显著升高，两组比较差异有统计学意义(P＜0.05)。术后2周，观察组的血清ACTH、Cor、TNF-α水平均明显低于对照组，且低于术前水平(P＜0.05)。结论：后路内固定融合术对胸腰段脊柱骨折患者椎体参数与创伤应激状态的影响相对更好。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the influence of posterior internal fixation and fusion on the vertebral body parameters and trauma stress state of patients with thoracolumbar spine fracture. Methods: 60 patients with thoracolumbar spine fracture during the time of November 2016 to November 2017 were selected for the study, and they were divided into control group(anterior internal fixation and fusion group) 30 cases and observation group(posterior internal fixation and fusion group) 30 cases. Then the variation of vertebral body parameters and serum ACTH, Cor and TNF-α of two groups before and after the operation were compared. Results: At one month and six months after surgery, the vertebral body parameters of the two groups were better than those before surgery, which were better in the observation group than those of the control group(P＜0.05). At one week after surgery, the level of serum ACTH, Cor of both groups were higher, which were lower in the observation group than those in the control group (P<0.05), the TNF-α level of observation group was lower in observation group than that of the control group(P<0.05). At two weeks after surgery, the serum ACTH level of observation group was much lower than those of the control group, which were even lower than those before surgery. The serum Cor and TNF-α levels of observation group were also lower than those of the control group(P<0.05). Conclusion: The influence of posterior internal fixation and fusion for the vertebral body parameters and trauma stress state of patients with thoracolumbar spine fracture are relatively better. |
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