| 蒲志忠,王红兵,邓 彬,郑伦辉,邹 辉.保肛术与腹会阴联合直肠癌根治术对低位直肠癌疗效及生活质量的比较研究[J].,2019,19(7):1332-1335 |
| 保肛术与腹会阴联合直肠癌根治术对低位直肠癌疗效及生活质量的比较研究 |
| Comparative Study on Curative Effect and Quality of Life of Anus Preserving Surgery and Abdominoperineal Radical Operation of Rectal Cancer for Low Rectal Cancer |
| 投稿时间：2018-09-26 修订日期：2018-10-20 |
| DOI：10.13241/j.cnki.pmb.2019.07.030 |
| 中文关键词: 保肛术 腹会阴联合直肠癌根治术 低位直肠癌 生活质量 疗效 预后 |
| 英文关键词: Anus preserving surgery Abdominoperineal radical operation of rectal cancer Low rectal cancer Quality of life Cura- tive effect Prognosis |
| 基金项目:重庆市卫生和计划生育委员会医学科研计划项目（2017MSXM194） |
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| 中文摘要: |
| 摘要 目的：比较保肛术与腹会阴联合直肠癌根治术（Miles术）对低位直肠癌患者的疗效及生活质量。方法：选取我院于2016年1月至2017年7月期间收治的低位直肠癌患者50例，按照乱数表法分为观察组与对照组，两组均为25例。观察组给予保肛术治疗，对照组给予Miles术治疗。对比两组患者围手术期情况以及术后并发症发生率，采用自制评分量表评价并对比两组患者术后的生活质量，随访1年，比较两组患者的复发率和1年生存率。结果：与对照组比较，观察组术中出血量、术后恢复正常排便时间、术后排气时间以及住院时间均降低（P<0.05）；与对照组比较，观察组生活质量优良率明显升高（P<0.05）；观察组术后并发症发生率明显低于对照组（P<0.05）；观察组盆腔复发率、吻合口复发率低于对照组，而1年生存率高于对照组（P<0.05）。结论：与Miles术比较，保肛术治疗低位直肠癌患者的临床疗效更好，患者术后恢复快、术后并发症发生率低，可明显改善患者的生活质量以及预后，值得临床推广应用。 |
| 英文摘要: |
| ABSTRACT Objective: To compare the curative effect and quality of life of anus preserving surgery and abdominoperineal radical operation of rectal cancer (Miles surgery) in patients with low rectal cancer. Methods: 50 patients with low rectal cancer who were treated in our hospital from January 2016 to July 2017 were selected, they were were divided into observation group and control group according to the random number table method, and two groups were 25 cases. The observation group was given anus preserving surgery, while the control group was treated with Miles surgery. The condition in perioperative period and the incidence of postoperative complications were compared between the two groups. Self rating scale was used to evaluate and compare the postoperative quality of life of the two groups. The recurrence rate and the 1 year survival rate of the two groups were compared after 1 years of follow-up. Results: Compared with the control group, the amount of bleeding during operation, the time to return to normal defecation, postoperative exhaust time and hospitalization time in the observation group were all decreased(P<0.05). Compared with the control group, the good and excellent rate of quality of life in the observation group was significantly increased(P<0.05). The incidence of postoperative complications in the obser- vation group was significantly lower than that in the control group(P<0.05). The pelvic recurrence rate and anastomotic recurrence rate of the observation group were lower than those of the control group, and the 1 year survival rate was higher than that of the control group (P<0.05). Conclusion: Compared with Miles surgery, clinical efficacy of anus preserving surgery is better in the treatment of low rectal cancer, postoperative recovery of patients is more quickly, and the incidence of postoperative complications is lower. It can significantly improve the quality of life and prognosis of patients, which is worthy of clinical application. |
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