| 张 琳,张贵祥,李念云,樊 莹,施靖蓉,张 皓,郑林丰.三维MRI用于高度近视眼球形态定量测量和后巩膜葡萄肿分型[J].,2018,(12):2283-2288 |
| 三维MRI用于高度近视眼球形态定量测量和后巩膜葡萄肿分型 |
| Pilot Study of Three Dimensional MRI in Evaluation of Eye Shape of High Myopia and Classification of Posterior Staphyloma |
| 投稿时间：2018-03-07 修订日期：2018-03-30 |
| DOI：10.13241/j.cnki.pmb.2018.12.017 |
| 中文关键词: 眼球 高度近视 后巩膜葡萄肿 磁共振成像 |
| 英文关键词: Eye High myopia Posterior staphyloma Magnetic resonance imaging (MRI) |
| 基金项目:上海市浦江人才计划项目(17PJ1408000)；上海市自然科学基金项目(17ZR1422500)；上海交通大学医工（理）交叉基金项目 |
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| 中文摘要: |
| 摘要 目的：研究运用三维磁共振成像（Three-Dimensional Magnetic Resonance Imaging，3D MRI）技术对高度近视的眼球形态进行定量测量以及后巩膜葡萄肿分型的可行性。方法：纳入我院129例共246个高度近视眼球（屈光度≥-600，眼轴长度≥26.0 mm）和50个正视眼（屈光度-100～100，正视眼组）。采用三维稳态进动快速采集成像序列（Three-Dimensional Fast Imaging Employing Steady-state Acquisition, 3D-FIESTA）扫描，扫描整个眼眶后获得的三维图像进行容积再现（Volume Rendering, VR）重建。评估眼球形态、后巩膜葡萄肿的形态和范围、与视神经的关系；测量眼球前后（AP）、左右（RL）、上下（SI）径线和RL/AP、SI/AP比值；根据后巩膜葡萄肿的形态和范围进行宽型和窄型分型。结果：246个高度近视眼球中，共100个眼球只表现为眼轴增长（眼轴增长组），146个表现为后巩膜葡萄肿（后巩膜葡萄肿组）。正视眼组、后巩膜葡萄肿组和眼轴增长组在AP径线上的差异有统计学意义(P<0.001)；反映眼球形变的比值RL/AP和SI/AP三组间的差异有统计学意义(P<0.001)。不同组间的年龄差异均有统计学意义（P<0.001）。146个后巩膜葡萄肿中宽型葡萄肿111个和窄型葡萄肿35个。结论：3D MRI可定量测量评估高度近视眼球的形态，诊断后巩膜葡萄肿并对其进行分型。 |
| 英文摘要: |
| ABSTRACT Objective: To study feasibility of quantitatively measurement shape of high myopia eyes and classification of posterior staphyloma using three-dimensional magnetic resonance imaging (3D MRI). Methods: 246 eyes with high myopia (Diopter≥-600 and axial length ≥26.0 mm) in 129 patients and 50 emmetropia (Diopters -100 to 100, emmetropic eye group) were included in our hospital. Then using three-dimensional fast imaging employing steady-state acquisition (3D-FIESTA) sequence and MR scanner, we acquired three-dimensional image data covering entire orbit and reconstructed with volume rendering (VR) by workstation. Next, we evaluated eye morphology, shape and extent of posterior staphyloma and relationship of posterior staphyloma with the optic nerve. In addition, length of anterior to posterior (AP), left to right (RL), and superior to inferior (SI) for every eye were measured and the ratios of RL/AP and SI/AP were calculated. Finally, we classified the posterior staphyloma as broad and narrow type according to shape and extent of staphy- loma. Results: Of the 246 high myopia eyes, 100 eyes showed only axial elongation (axial elongation group), and 146 showed posterior staphyloma (posterior staphyloma group). There was a statistically significant difference in AP line length, ratio of RL/AP and SI/AP(re- flected eye ball deformation) among the emmetropic eye group, the posterior staphyloma group and the axial elongation group (P<0.001). The age differences between these three different groups were statistically significant (P<0.001). Of the 146 posterior staphyloma, 111 were wide-type staphylomas and 35 were narrow-type staphylomas. Conclusion: 3D MRI is a useful tool to measure quantitatively the morphology of high myopia eyes, diagnose and classify the posterior staphyloma. |
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