文章摘要
毛陇萍,杨 红,程 娟,张 静,王 莲,王庆云.子痫前期发病相关高危因素的Logistic回归分析[J].,2018,(10):1982-1985
子痫前期发病相关高危因素的Logistic回归分析
Logistic Regression Analysis of High Risk Factors Related to Preeclampsia
投稿时间:2017-10-12  修订日期:2017-10-31
DOI:10.13241/j.cnki.pmb.2018.10.037
中文关键词: 子痫前期  Logistic回归分析  自然流产史  妊娠高血压
英文关键词: Preeclampsia  Logistic regression analysis  History of spontaneous abortion  Pregnancy induced hy- pertension
基金项目:宝鸡市科学技术奖项目(2013-330-G1)
作者单位E-mail
毛陇萍 西安医学院附属宝鸡医院妇产科 陕西 宝鸡 721006 maolongping_1976@medicinepap.cn 
杨 红 空军军医大学西京医院妇产科 陕西 西安 710032  
程 娟 西安医学院附属宝鸡医院妇产科 陕西 宝鸡 721006  
张 静 西安医学院附属宝鸡医院妇产科 陕西 宝鸡 721006  
王 莲 西安医学院附属宝鸡医院妇产科 陕西 宝鸡 721006  
王庆云 西安医学院附属宝鸡医院妇产科 陕西 宝鸡 721006  
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中文摘要:
      摘要 目的:采用单因素和多因素Logistic回归方法分析本地区子痫前期发病相关高危因素。方法:选择2014年1月到2017年4月在我院进行分娩的子痫前期产妇78例作为观察组及同期在我院进行分娩的正常产妇78例作为对照组,比较两组产妇的一般情况、婚姻生育史、孕期保健情况、既往史、家族史、本次妊娠情况等。结果:两组产妇的年龄、孕次、产次、初检孕周、产前检查次数等比较差异无统计学意义(P>0.05)。观察组子痫前期首次发生的平均孕周为38.26±2.63周。单因素分析显示自然流产史、子痫前期家族史、妊娠高血压、孕前BMI、孕期尿路感染与子痫前期发病明显相关(P<0.05);非条件Logistic回归多因素分析结果显示自然流产史、子痫前期家族史、妊娠高血压、孕前BMI为导致子痫前期发病的主要独立危险因素(P<0.05)。观察组以剖宫产为主要分娩方式,分娩孕周也明显长于对照组(P<0.05);两组产妇都无死亡情况发生,但观察组的产后出血、胎盘早剥、心肝肾功能不全等并发症发生率明显高于对照组(P<0.05)。结论:自然流产史、子痫前期家族史、妊娠高血压、孕前BMI为导致子痫前期发病的主要独立危险因素,可导致不良妊娠结局的增加。
英文摘要:
      ABSTRACT Objective: To investigate the risk factors of preeclampsia in our region by single factor and multiple factor Logistic re- gression analysis. Methods: From January 2014 to April 2017, 78 cases of preeclampsia for delivery in our hospital were selected as the observation group, and the other 78 cases of normal delivery in our hospital were selected as the control group, the general situation, ma- ternal marriage and childbearing history, prenatal care, medical history and family history the pregnancy situation of both groups were in- vestigated. Results: There was no significant difference in the age, number of pregnancies, times of birth, initial pregnancy, and times of prenatal diagnosis between the two groups (P>0.05). The average gestational age for the first occurrence of preeclampsia in the observa- tion group was 38.26±2.63 weeks. Univariate analysis showed that history of spontaneous abortion, preeclampsia, gestational hyperten- sion, family history of BMI before pregnancy and urinary tract infection and the pathogenesis were significantly correlated to the preeclampsia (P<0.05). Non conditional Logistic regression analysis showed that the history of spontaneous abortion, preeclampsia, preg- nancy, family history of hypertension of pregnancy BMI leading were the independent risk of preeclampsia (P<0.05). More cesarean sec- tion was found in the observation group, the gestational weeks were significantly longer than that of the control group(P<0.05); no death occurred in both groups, but the incidence of postpartum hemorrhage, placental abruption, liver and kidney insufficiency in the observa- tion group was higher than that of the control group (P<0.05). Conclusion: The history of spontaneous abortion, preeclampsia, gestational hypertension, family history of pregnancy BMI are the independent risk of preeclampsia may increase adverse pregnancy outcomes.
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