| 胥 丹,刘 苏,孙乾伟,徐 敏,王 昱,齐敦益.布托啡诺复合右美托咪定抑制剖宫产术后宫缩痛的临床效果观察[J].,2018,(8):1519-1522 |
| 布托啡诺复合右美托咪定抑制剖宫产术后宫缩痛的临床效果观察 |
| Inhibitory Effect of Bhutto Butorphanol Combined with Dexmedetomidine on the Constriction Pain after Cesarean Section |
| 投稿时间：2017-10-20 修订日期：2017-11-12 |
| DOI：10.13241/j.cnki.pmb.2018.08.024 |
| 中文关键词: 布托啡诺 右美托咪定 剖宫产 宫缩痛 不良反应 |
| 英文关键词: Bhutto Butorphanol Dexmedetomidine Cesarean section Uterine contraction pain Adverse reactions |
| 基金项目:江苏省自然科学基金面上项目 （BK2011198） |
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| 中文摘要: |
| 摘要 目的：观察布托啡诺复合右美托咪定抑制剖宫产术后宫缩痛的临床效果及安全性。方法：将2015年7月到2016年10月在我院进行建档分娩的剖宫产产妇84例作为研究对象，根据随机信封抽签原则分为观察组与对照组，每组各42例。两组都给予腰硬联合麻醉，对照组给予术后右美托咪定镇痛，观察组给予术后布托啡诺复合右美托咪定镇痛，记录和比较两组产妇的宫缩痛情况。结果：两组新生儿的Apgar评分对比差异无统计学意义(P>0.05)，所有新生儿都存活。术后2h、4h与24h，观察组的宫缩痛评分分别为0.46±0.14分、0.82±0.19分和2.44±0.92分，都明显低于对照组的5.44±0.98分、5.63±0.78分和6.09±0.99(P<0.05)。观察组术后恶心、呕吐、皮肤瘙痒、呼吸抑制等不良反应发生率为9.5%，对照组为11.9%，两组对比差异无统计学意义(P>0.05)。观察组与对照组出院时镇痛满意度分别为100.0%和90.5%，观察组的满意度明显高于对照组(P<0.05)。结论：布托啡诺复合右美托咪定能更好抑制剖宫产术后宫缩痛，对新生儿无明显影响，且安全性较高。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the clinical efficacy and safety of Bhutto and Butorphanol in combination with dexmedetomidine in the prevention of constriction pain after cesarean section. Methods: From July 2015 to October 2016, 160 cases of cesarean section in our hospital for document delivery were selected as the research object, all the cases were randomly divided into the observation group and the control group with 80 cases in each group according to the random lottery envelopes, both groups were given combined spinal epidural anesthesia, the control group was given postoperative analgesia of dexmedetomidine, the observation group was given postoperative analgesia of Bhutto butorphanol combined with dexmedetomidine, the postoperative uterine contraction pain in the two groups were recorded and compared. Results: No significant difference was found in the Apgar score of newborns between two groups(P>0.05), all the newborns survived. The uterine contraction pain scores in the observation group at 2h, 4h and 24h postoperation were 0.46±0.14 points, 0.82±0.19 points and 2.44±0.92 points, which were all significantly lower than those of the control group(5.44± 0.98 points, 5.63±0.78 points and 6.09±0.99)(P<0.05). The incidence of adverse reactions such as nausea, vomiting, pruritus and respiratory depression in the observation group was 8.8%, which was 10.0% in the control group, and there was no significant difference between the two groups (P>0.05). The satisfaction degree of analgesia in the observation group and the control group was 100% and 92.2% respectively, which was higher in the observation group than that of the control group (P<0.05). Conclusion: Bhutto butorphanol combined dexmedetomidine could better inhibit the cesarean section uterine contraction pain, it had no significant effect on the newborn, and had good safety. |
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