| 钟 武,孙清超,张海平,王志鹏,张昌明,邓彦超.经胸腔镜与开胸手术治疗胸腺瘤合并重症肌无力的临床疗效比较[J].,2018,(6):1124-1128 |
| 经胸腔镜与开胸手术治疗胸腺瘤合并重症肌无力的临床疗效比较 |
| Comparison of the Clinical Efficacy of Thoracoscopic Surgery and Thoracotomy in the Treatment of Thymoma Complicated with Myasthenia Gravis |
| 投稿时间：2017-11-08 修订日期：2017-11-30 |
| DOI：10.13241/j.cnki.pmb.2018.06.026 |
| 中文关键词: 胸腔镜 开胸 胸腺瘤 重症肌无力 疗效 |
| 英文关键词: Thoracoscopy Thoracotomy Thymoma Myasthenia gravis Efficacy |
| 基金项目:新疆维吾尔自治区自然科学基金项目(2016D01C322) |
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| 中文摘要: |
| 摘要 目的：观察和比较经胸腔镜与开胸胸腺瘤扩大切除术治疗胸腺瘤伴重症肌无力(MG)患者的临床疗效和安全性。方法：回顾性分析2010年1月至2015年12月在新疆医科大学附属第一医院胸外科接受胸腔镜手术与开胸手术(本研究指胸骨正中劈开胸腺瘤扩大切除术)共120例胸腺瘤伴MG患者的临床资料，比较两组的手术时间、术后并发症、术后WHO病理分型、Masaoka分期、术后MGFA分级、远期随访总缓解率、术中出血量、术后拔管时间、术后住院天数和术后VAS疼痛评分。结果：两组手术时间、术后并发症、术后WHO病理分型、Masaoka分期、术后MGFA分级及远期随访总缓解率比较差异均无统计学意义(P＞0.05)；开胸组肿瘤直径明显大于胸腔镜组，胸腔镜组术中出血量、术后拔管时间、术后住院天数和术后VAS疼痛评分明显短于或低于开胸组，差异均有统计学意义(P＜0.05)。结论：经胸腔镜与开胸胸腺瘤扩大切除术治疗MG的远期疗效相当，但胸腔镜手术创伤更小，有利于减少术后疼痛并加快患者恢复。 |
| 英文摘要: |
| ABSTRACT Objective: To observe and compare the clinical efficacy and safety between thoracoscopic thoracotomy and thoracic thoracotomy in the treatment of thymoma with myasthenia gravis (MG). Methods: The clinical data of 120 cases of patients with thymoma and MG underwent thoracoscopic surgery and thoracotomy surgery (this study referred to the middle of the sternum split thymoma enlargement resection) in the Department of Thoracic Surgery of the First Affiliated Hospital of Xinjiang Medical University from January 2010 to December 2015 were retrospectively analyzed. The operation time, incidence of postoperative complications, postoperative WHO pathological classification, Masaoka stage, postoperative MGFA classification, long-term follow-up total remission rate, intraoperative blood loss, postoperative extubation time, postoperative hospital stay And postoperative VAS pain score were compared between two groups. Results: There was no significant difference in the operation time, postoperative complications, postoperative WHO pathological classification, Masaoka stage, postoperative MGFA grade and long term follow up overall remission rate between the two groups(P>0.05); the tumor diameter of thoracotomy group was significantly larger than that of the thoracoscopic group, the intraoperative blood loss, postoperative extubation, postoperative hospital stay and postoperative VAS pain score of thoracoscopic group were significantly shorter or lower than those of the thoracic group(P<0.05). Conclusion: Thoracoscopy and thoracic thoracic extension resection had equal efficacy in the treatment of thymoma complicated with MG, but thoracoscopic surgery had less thoracic surgery trauma, postoperative pain and promote the rapid recovery of patients. |
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