| 何盛为,陈秉智,秦睿贤,杜广宇,米立东.经皮椎体成形术对骨质疏松性胸腰椎骨折患者生物力学的影响研究[J].,2018,(4):705-708 |
| 经皮椎体成形术对骨质疏松性胸腰椎骨折患者生物力学的影响研究 |
| Effects of Percutaneous Vertebroplasty on Biomechanics of Patients with Osteoporotic Thoracolumbar Fractures |
| 投稿时间：2017-04-29 修订日期：2017-05-25 |
| DOI：10.13241/j.cnki.pmb.2018.04.022 |
| 中文关键词: 骨质疏松 胸腰椎骨折 经皮椎体成形术 生物力学 影响 |
| 英文关键词: Osteoporosis Thoracolumbar fractures Percutaneous vertebroplasty Biomechanics Effects |
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| 中文摘要: |
| 摘要 目的：探讨经皮椎体成形术对骨质疏松性胸腰椎骨折患者生物力学的影响。方法：选取9具冻存新鲜尸体的胸腰段脊柱开展研究，并应用随机数字表法分为观察组、对照1组和对照2组，每组各3具。观察组、对照1组均制作成骨质疏松性胸腰椎骨折模型，观察组经椎弓根注入含有对比剂的低粘度骨水泥，对照1组置入椎弓根螺钉内固定，分别于术前和术后测量两组椎体的主要生物力学指标（最大抗压强度、刚度、高度），对照2组则作为参照，仅测量一次，对三组生物力学指标检测结果进行统计分析。结果：观察组椎体术前的最大抗压强度、刚度、高度与对照1组比较差异无统计学意义（P>0.05），但两组术前最大抗压强度、刚度较对照2组降低，而高度较对照2组升高（P<0.05）。观察组和对照2组术后的最大抗压强度、刚度均较对照1组升高，高度较对照1组降低（P<0.05），而观察组术后的最大抗压强度、刚度、高度与对照2组比较差异无统计学意义（P>0.05）。结论：应用经皮椎体成形术对骨质疏松性腰椎骨折患者实施治疗，能够有效恢复患者椎体生物力学，效果确切。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effects of percutaneous vertebroplasty on the biomechanics of patients with osteoporotic thoracolumbar fractures. Methods: A total of 9 frozen fresh cadavers of the thoracolumbar spine were selected for this research and randomly divided into observation group(n=3), control group 1(n=3) and control group 2(n=3). The observation group and the control group 1 were made into osteoporotic thoracolumbar fracture models; the observation group was injected with low viscosity bone cement with contrast medium, and the control group 1 was treated with pedicle screw fixation; the main biomechanical indexes (maximum compressive strength, stiffness and height) of the two groups were measured before and after operation. The control group 2 was taken as a reference only, measured only once. The detection results of biomechanical indexes of the three groups were statistically analyzed. Results: There were no significant differences in the maximum compressive strength, stiffness and height before operation between the observation group and the control group 1 (P>0.05). However, the maximum compressive strength and stiffness of the two groups were lower than those of the control group 2, and the height was higher than that of the control group 2 (P<0.05). After operation, the maximal compressive strength and stiffness of the observation group and the control group 2 were higher than those of the control group 1, and the height was lower than that of the control group 1 (P<0.05), while there were no significant differences in the maximum compressive strength, stiffness and height after operation between the observation group and the control group 2 (P>0.05). Conclusion: The application of percutaneous vertebroplasty in the treatment of osteoporotic vertebral fractures can effectively restore the biomechanical properties of patients, and the effects are exact. |
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