| 才让卓玛,陈秀英,连心龙,景林德,刘建菊.急性心肌梗死患者心脏介入治疗后血小板与嗜酸性粒细胞变化情况及相关性研究[J].,2017,17(34):6756-6759 |
| 急性心肌梗死患者心脏介入治疗后血小板与嗜酸性粒细胞变化情况及相关性研究 |
| Acute Myocardial Infarction: Changes of Platelet and Eosinophils and Their Correlation Analysis after Cardiac Interventional Therapy |
| 投稿时间：2017-08-15 修订日期：2017-08-31 |
| DOI：10.13241/j.cnki.pmb.2017.34.034 |
| 中文关键词: 急性心肌梗死 心脏介入 血小板 嗜酸性粒细胞 相关性 |
| 英文关键词: Acute myocardial infarction Cardiac interventional Platelet Eosinophils Correlation |
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| 中文摘要: |
| 摘要 目的：观察急性心肌梗死患者心脏介入治疗后外周血小板（PLT）和嗜酸性粒细胞（EOS）的变化，并以此来推断两者在急性心梗死中可能发生的作用。方法：选择2015年1月至2017年1月期间于我院就诊并明确诊断为急性心肌梗死的患者86例作为观察组，同时选择于我院行冠脉造影证实无心肌梗死的冠心病患者30例作为对照组。分别在术前、术后以及术后三天进行抽血检测血常规及肌钙蛋白（cTnT）。结果：两组患者在年龄、性别、体质量以及是否有糖尿病病史方面无统计学差异（P>0.05），但在是否有烟酒史、高血压病史、cTnT等方面，观察组患者占有更高的比例，差异具有统计学意义（P<0.05）。观察组患者术前PLT数量显著高于对照组，术后两组患者PLT均呈逐步下降趋势，至术后第三天，两组患者PLT水平基本相同，无统计学差异（P>0.05）。观察组患者术前EOS数量显著低于对照组，术后EOS呈逐步上升趋势，至术后第三天，两组患者EOS水平基本相同，无统计学差异（P>0.05）。结论：急性心肌梗死患者中是否有烟酒史、高血压病史对其影响较大，同时在本病的发生过程中与PLT升高、EOS降低有着密切的关系。 |
| 英文摘要: |
| ABSTRACT Objective: To observe the changes of peripheral platelet (PLT) and eosinophil (EOS) in patients with acute myocardial infarction after cardiac interventional therapy, and to infer the possible effect of them in acute myocardial infarction. Methods: A total of 86 patients with acute myocardial infarction, who were diagnosed and treated in Qinghai People's Hospital during January 2015 to January 2017, were chosen as observation group. At the same time, 30 patients with coronary artery disease, without myocardial infarction convinced by coronary angiography, were chosen as control group. Before operation, after operation and three days after operation, the blood samples were taken for blood routine and cardiac troponin T (cTnT) examination. Results: There were no statistical differences in age, gender, weight and history of diabetes mellitus between the two groups(P>0.05). However, the patients in the observation group had higher proportion in the history of alcohol and tobacco, history of hypertension, cTnT and so on, the differences were statistically significant (P<0.05). Before operation, the level of PLT in the observation group was significantly higher than that in the control group. After operation, the levels of PLT in the two groups showed gradually downward trend. Three days after operation, the PLT levels were basically the same in the two groups, which had no statistical difference (P>0.05). Before operation, the level of EOS in the observation group was significantly lower than that in the control group. After operation, the level of EOS showed gradually upward trend.Three days after operation, the EOS levels were basically the same in the two groups, which had no statistical difference (P>0.05). Conclusion: The history of alcohol and tobacco and the history of hypertension have great influence on the patients with acute myocardial infarction, which has close relationship with the increase of PLT and the decrease of EOS in the course of the disease. |
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