| 余小林,范 昊,关 娜,李国庆,穆叶塞·尼加提.心外膜脂肪厚度与冠脉病变严重程度的相关性研究[J].,2017,17(30):5921-5924 |
| 心外膜脂肪厚度与冠脉病变严重程度的相关性研究 |
| Correlative Analysis of Epicardial Adipose Tissue Thickness with the Severity of Coronary Atherosclerotic Heart Disease |
| 投稿时间：2017-07-04 修订日期：2017-07-30 |
| DOI：10.13241/j.cnki.pmb.2017.30.028 |
| 中文关键词: 心外膜脂肪组织 Gensini评分 Syntax评分 超声心动图 |
| 英文关键词: Epicardial adipose tissue(EAT) Gensini score Syntax score Ultrasonic cardiogram |
| 基金项目:国家自然科学基金项目（811600029） |
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| 中文摘要: |
| 摘要 目的：探讨心外膜脂肪组织(Epicardial adipose tissue，EAT)厚度与冠状动脉病变严重程度的相关性。方法：收集167名符合纳入标准的患者，根据冠状动脉造影(coronary arteriography，CAG)结果分2组：正常冠脉组（65例）及冠心病冠脉病变组(≥1支冠状动脉病变狭窄程度≥50%)（102例）。同期经胸超声心动图测量EAT厚度，并依据CAG图像计算Gensini评分、Syntax评分。结果：冠脉正常组和冠心病病变组EAT厚度分别为(3.89±0.2 mm)、(6.19±1.19 mm)，冠心病病变组显著高于冠脉正常组(P<0.001)。进一步分析EAT的厚度分别为< 5 mm、5 - 7 mm和> 7 mm时，Gensini评分分别为：7.21±7.73,37.80±29.55和62.77±27.26；Syntax评分分别为：7.13±7.70,19.71±7.27和24.95±4.31。EAT的厚度与Gensini评分(r=0.621；P<0.001)、Syntax评分(r=0.689；P<0.001)呈正相关。结论：心外膜脂肪组织厚度与冠状动脉狭窄的复杂程度评分Gensini评分、Syntax评分呈正相关。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the correlation of thickness of epicardial adipose tissue (EAT) with the severity of coronary artery stenosis. Methods: 167 cases of patients were selected and allocated into 2 groups according to the coronary angiography(coronary arteriography, the CAG), normal coronary group（n=65cases） and coronary heart disease lesion group(1 coronary artery lesions in 50% or higher) or higher（n=102 cases）. Thoracic echocardiography was used to measure the EAT thickness and review the CAG image Gensini score. Results: The thickness of the EAT in the normal coronary group and coronary heart disease lesion group were 3.89±0.2 mm, 6.19 ± 1.19 mm, which was significantly higher in the coronary heart disease group (P<0.001). The mean Gensini score of patients with thickness of EAT <5, 5-7 and >7 mm were 7.21±7.73, 37.80 ± 29.55 and 29.55 ±27.26; the Syntax score were 7.13 ±7.70, 19.71±7.27 and 7.27 ±4.31. The EAT thickness and Gensini score (r = 0.621; P < 0.001), the Syntax score (r = 0.689, P < 0.001), and pathological changes of coronary heart disease were associated with the severity of coronary artery stenosis. Conclusion: EAT thickness and the complexity of the coronary artery stenosis and Gensini score, Syntax score. |
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