| 吕功伟,钟 镝,赵秀丽,石于波,李国忠.进展性缺血性卒中预后的相关因素分析[J].,2017,17(29):5781-5787 |
| 进展性缺血性卒中预后的相关因素分析 |
| Analysis about Related Factors of Prognosis in Progressive Ischemic Stroke Patients |
| 投稿时间：2017-05-31 修订日期：2017-06-25 |
| DOI：10.13241/j.cnki.pmb.2017.29.043 |
| 中文关键词: 进展性缺血性卒中 预后 危险因素 二级预防 |
| 英文关键词: Progressive ischemic stroke Prognosis Risk factor Secondary prevention |
| 基金项目:国家卫生和计划生育委员会重点临床专科建设项目（2012-649号） |
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| 中文摘要: |
| 摘要 目的：探究进展性缺血性卒中预后的相关危险因素。方法：选取进展性缺血性卒中患者98例，根据复发情况将患者分为复发组和无复发组，分析进展性缺血性卒中复发与二级预防的关系。无复发组的患者按根据随访的mRS评分高低分为：预后良好组(mRS 0～2分)和预后差组(mRS 3～5分)，分析影响预后的相关因素。结果：结论：良好的二级预防依从性有利于降低进展性缺血性卒中的复发率。入院时白细胞计数、LDL、血糖是影响进展性缺血性卒中预后的相关因素。入院时白细胞计数、LDL及空腹血糖值较高的进展性缺血卒中患者，其预后往往较差。 |
| 英文摘要: |
| ABSTRACT Objective: To analyze the possible risk factors of progressive ischemic stroke prognosis. Methods: 98 progressive is- chemic stroke patients were selected and according to the recurrence, the patients were divided into the recurrent group and the non re- current group. Then the relationship between recurrence and secondary prevention was analyzed. The patients in the non recurrent group were divided into the good prognosis group with mRS score from 0 to 2 and bad prognosis group with mRS score from 3 to 5. Then the relationship between prognosis and risk factors at 1st, 3rd and 6th month post discharge were analyzed. Results: The recurrent rate of the progressive ischemic stroke patients was 10.2%(10/98) in six months. Compared with the recurrent group, the patients in the non recur- rent group continued to use secondary prevention medications such as anti-hypertensive drugs, antidiabetes drugs, antiplatelet drug and lipid lowing drugs post discharge, and the difference was statistically significant (P<0.05). In non recurrent group at 1st, 3rd and 6th month discharged, the levels of white blood cell count, LDL and glucose were correlated with prognosis (P<0.05). According to the multivari- able logistic regression analysis, the levels of white blood cell count, LDL and glucose were the risk factors of poor prognosis at 1st month post discharge, the levels of white blood cell count and glucose were the risk factors of poor prognosis at 3rd month post dis- charge, and the levels of LDL and glucose were the risk factors of poor prognosis at 6th month after discharge. Conclusion: Secondary prevention is good for reducing the recurrence rate of progressive ischemic stroke. The levels of white blood cell count, LDL and glucose are the risk factors of progressive ischemic stroke prognosis. The higher levels of white blood cell and LDL and glucose might be the main risk fac- tors of poor prognosis. |
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