| 胡伟卓,刘忠虎,秦红娟,齐 辉,张 雷.不同分化程度的原发性肝癌MRI初步临床研究[J].,2017,17(26):5074-5078 |
| 不同分化程度的原发性肝癌MRI初步临床研究 |
| Preliminary Clinical Study of MRI in Primary Hepatic Cancer with Different Differentiation |
| 投稿时间：2017-01-08 修订日期：2017-01-31 |
| DOI：10.13241/j.cnki.pmb.2017.26.015 |
| 中文关键词: 肝硬化 肝癌 肝内胆管癌 病理 磁共振成像 |
| 英文关键词: Cirrhosis Hepatic cancer Cholangiocarcinoma Pathology Magnetic resonance imaging |
| 基金项目:宝鸡市卫计局科研项目（2015-65） |
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| 摘要点击次数: 91 |
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| 中文摘要: |
| 摘要 目的：探讨原发性肝癌不同分化程度、细胞类型的MRI图像特征、参数。方法：回顾性分析肝硬化再生结节27例、肝细胞癌75例81处病灶（高度分化15例，中度分化40例，低度分化26例）、肝内胆管癌20例的病理结果及MRI影像学数据，比较再生结节、肝细胞癌和肝内胆管癌之间，以及肝细胞癌各种组织分化程度之间的ADC值、强化程度差异。结果：常规MRI平扫结合LAVA可准确诊断大部分原发性肝癌病例。再生结节、肝细胞癌及肝内胆管癌ADC值均值的具有显著统计学差异（P<0.01）；肝细胞癌高分化组、中分化组及低分化组ADC值均值均具有显著统计学差异（P<0.01），但中、低分化肝细胞癌ADC值均值的差异无实际临床意义；高分化肝细胞癌与肝内胆管癌ADC值均值的差异无统计学意义（P=0.27）。结论：常规MRI结合DWI、多期动态增强扫描有助于区分原发性肝癌各种组织分化程度及细胞类型。 |
| 英文摘要: |
| ABSTRACT Objective: To study parameters of MRI image in different tissue differentiation, cell type of primary liver cancer. Methods: The pathological results and MRI data of regeneration nodules(27), hepatocellular carcinoma(HCC) (81 total; 15, highly differentiated; 40, moderately differentiated; 26, low-grade differentiation), intrahepatic cholangiocarcinoma(ICC) (20) were retrospectively analyzed and compared To compare the difference of ADC values, strengthen degree among the regeneration nodules, HCC and ICC, and among HCC tissue differentiation. Results: Most cases of primary liver cancer can be accurately diagnosed by conventional MRI combined with LAVA. there are statistically significant differences of ADC values among regenerative nodules, HCC, ICC (P<0.01), and among highly, moderately, poorly differentiated HCC groups (P<0.01). But there is not actual clinical significance of the ADC values between moderately and poorly HCC. there is no statistically significant difference of the ADC values between highly differentiated HCC and ICC (P=0.27). Conclusion: Conventional MRI combining with DWI, LAVA can help distinguish the primary liver cancer differentiation degree and the cell type. |
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