| 孙淋霞,马 敏,金腊梅,佘琼华,晏 娟,贺 勇.红细胞分布宽度血小板比率和中性粒细胞淋巴细胞比率在急诊PCI术后冠脉无复流评估中的应用价值[J].,2017,17(25):4856-4859 |
| 红细胞分布宽度血小板比率和中性粒细胞淋巴细胞比率在急诊PCI术后冠脉无复流评估中的应用价值 |
| Clinical Value of Platelet Distribution Width Ratio and Neutrophil Lymphocyte Ratio in the Evaluation of Coronary No-Reflow in Patients Treated by Emergency PCI |
| 投稿时间：2017-04-10 修订日期：2017-04-30 |
| DOI：10.13241/j.cnki.pmb.2017.25.013 |
| 中文关键词: 红细胞分布宽度血小板比率 中性粒细胞淋巴细胞比率 急诊经皮冠状动脉介入 冠状动脉 无复流 |
| 英文关键词: Red blood cell distribution width platelet ratio Neutrophil lymphocyte ratio Emergency percutaneous coronary inter- vention Coronary artery No reflow |
| 基金项目:四川省科技厅应用基础重点项目（2017JY0026） |
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| 中文摘要: |
| 摘要 目的：探讨红细胞分布宽度血小板比率(RDW)和中性粒细胞淋巴细胞比率(NLR)预测急诊经皮冠状动脉介入（PCI）术后冠脉无复流的应用价值。方法：选取2016年1月～2016年12月于我院行急诊PCI手术治疗的患者66例为研究对象，检测其治疗前的RDW和NLR，统计其急诊PCI术后冠脉无复流现象的发生情况，比较冠脉无复流和正常血流患者的RDW和NLR，分析患者RDW和NLR与其冠脉无复流的关系及其对冠脉无复流的预测价值。结果：66例患者急诊PCI术后冠脉无复流发生率为30.30%(20/66)。与正常血流患者比较，冠脉无复流患者RDW和NLR均升高(P＜0.05)。Spearman相关分析结果显示患者RDW和NLR与其冠脉无复流均呈正相关(r=0.826，0.878，P＜0.05)。进一步ROC曲线分析结果显示急诊PCI术前RDW和NLR联合预测其术后冠脉无复流的的ROC曲线下面积高于二者单独预测。结论：急诊PCI患者RDW和NLR与其术后冠脉无复流密切相关且两者联合预测患者术后冠脉无复流的价值良好，可能作为急诊PCI术后冠脉无复流评估的参考指标。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the clinical value of platelet distribution width ratio (RDW) and neutrophil lymphocyte ratio (NLR) in the prediction of coronary no reflow in patients treated with acute percutaneous coronary intervention(PCI). Methods: 66 pa- tients underwent emergency PCI treatment in our hospital from January 2016 December 2016 were selected as the research object, RDW and NLR of the patients before treatment were detected, and coronary no reflow phenomenon after emergency PCI rate were statistically calculated. RDW and NLR of patients with no reflow and normal blood flow were compared, the relationship between RDW and NLR with no reflow and the value of them predicting coronary no reflow were analyzed. Results: The incidence of coronary no reflow after emergency PCI was 30.30% (20/66). Compared with patients with normal blood flow, the RDW and NLR of patients with coronary no reflow were elevate (P＜0.05). Spearman correlation analysis results showed that RDW and NLR were positively correlated with coro- nary no reflow (r=0.826, 0.878, P＜0.05). Further ROC curve analysis showed that AUC of preoperative RDW combined with NLR pre- dicting the postoperative coronary no reflow in patients treated with emergency PCI were higher than RDW and NLR alone. Conclusion: RDW and NLR in patients treated with emergency PCI were closely related to the postoperative coronary no reflow, which might be used as reference index for evaluation of coronary no reflow after emergency PCI. |
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