| 程延娜,安 智,贺晓丽,郑 娜,刘 鹏.血液净化治疗肾综合征出血热合并急性肾功能衰竭的疗效分析[J].,2017,17(22):4346-4348 |
| 血液净化治疗肾综合征出血热合并急性肾功能衰竭的疗效分析 |
| Therapeutic Effect of Blood Purification on Hemorrhagic Fever with Renal Syndrome Combined with Acute Renal Failure |
| 投稿时间：2016-10-23 修订日期：2016-11-15 |
| DOI：10.13241/j.cnki.pmb.2017.22.035 |
| 中文关键词: 肾综合征出血热 急性肾功能衰竭 血液透析 |
| 英文关键词: Hemorrhagic fever with renal syndrome Acute renal failure Hemodialysis |
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| 中文摘要: |
| 摘要 目的：探讨血液净化治疗肾综合征出血热合并急性肾功能衰竭的疗效。方法：选取了60例肾综合征出血热合并急性肾功能衰竭患者，按住院单双号分为两组，观察组(31例) 采用血液透析治疗，对照组(29例) 采用连续性静脉-静脉血液滤过法治疗，观察并记录两组患者肾功能相关指标、血清离子、血常规相关指标及治疗期间不良反应情况，评估血液净化治疗肾综合征出血热合并急性肾功能衰竭的疗效。结果：治疗前两组K+、HCO3-、血尿素氮(BUN)、血清肌酐(Cr)等指标无统计学差异(P>0.05)，治疗后两组K+、BUN、Cr等指标均明显降低，且观察组上述指标低于对照组(P<0.05)；治疗后两组HCO3-水平升高，且观察组高于对照组(P<0.05)，治疗前，两组血红蛋白(Hb)，红细胞压积(Hct)，血小板(PLT)无统计学差异(P>0.05)，治疗后两组Hb，Hct，PLT均升高(P<0.05)，但组间比较没有统计学差异(P>0.05)，随访1年期间，观察组患者6个月和12个月生存率明显高于对照组(P<0.05)。治疗期间，两组不良反应率无统计学差异(P>0.05)。结论：血液透析对肾综合征出血热合急性肾功能衰竭具有较好的治疗效果，能调节体内电解质平衡，改善肾功能，提高生存率，改善血液状态的效果与连续性静脉-静脉血液滤过法相当。 |
| 英文摘要: |
| ABSTRACT Objective: To discuss the therapeutic effect of blood purification on hemorrhagic fever with renal syndrome combined with acute renal failure. Methods: 60 patients with hemorrhagic fever with renal syndrome combined with acute renal failure were selected, and they were divided into two groups according to the odd and even number of hospitalization. The observation group (31 cases) received hemodialysis therapy. The control group (29 cases) received veno-venous hemofiltration therapy. The renal function, serum ion, blood routine indexes and the incidence of adverse reactions during treatment was detected and compared between two groups. Results: There were no statistical significance on K+, HCO3-, BUN, Cr between two groups (P>0.05). After treatment, the K+, BUN, Cr levels were decreased in two groups (P<0.05). The values of observation group were lower than those of the control group (P<0.05). The level of HCO3- was increased in two groups, and it was higher in observation group than that of the control group (P<0.05). Before treatment, there was no statistical significance on Hb, Hc, PLT between two groups (P>0.05). After treatment, the Hb, Hc, PLT levels were increased in two groups (P<0.05), but there were no statistical significance between two groups (P>0.05). During 1 year of follow-up, the 6 months and 12 months survival rate of observation group was higher than that of the control group(P<0.05). During treatment, there were no statistical significance on the incidence of adverse reactions between two groups (P>0.05). Conclusion: The hemofiltration therapy has a good therapeutic effect on blood purification on hemorrhagic fever with renal syndrome combined with acute renal failure, and it can regulate the electrolyte balance, improve the renal function and increase the survival rate, which is equivalent to veno-venous hemofiltration therapy in amelioration of blood state. |
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