| 董建新,韩翠娜,王 艳,江春花,王怡佳.宫颈上皮内瘤变Ⅲ级术后随诊情况及其临床结局分析[J].,2017,17(19):3715-3718 |
| 宫颈上皮内瘤变Ⅲ级术后随诊情况及其临床结局分析 |
| Analysis of the Clinical Outcome and Follow-up Results of Patients with Cervical Intraepithelial Neoplasia Grade Ⅲ |
| 投稿时间：2016-12-06 修订日期：2016-12-30 |
| DOI：10.13241/j.cnki.pmb.2017.19.029 |
| 中文关键词: 宫颈上皮内瘤变Ⅲ级 术后随诊 HR-HPV 宫颈液基细胞学检查 |
| 英文关键词: Cervical intraepithelial neoplasia grade Ⅲ Postoperative follow - up HR-HPV TCT |
| 基金项目:河北省卫生厅医学科学研究重点项目(201607260) |
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| 中文摘要: |
| 摘要 目的：探讨宫颈上皮内瘤变Ⅲ级患者宫颈冷刀锥切术后的随访情况，并行TCT及HR-HPV监测对随诊情况进行分析。方法：选择我院2013年6月至2015年6月收治的宫颈冷刀锥切术后诊断为宫颈高级别上皮内瘤变(CINIII，HR-HPV阳性)的患者共计150例，分别于锥切术后3、6、12个月进行HR-HPV检测、宫颈液基细胞学(TCT)检查，并分析其随访情况。结果：不同年龄段患者正规随访比例分别为73.91%、78.05%、68.09%、75%，差异无统计学意义(P>0.05)。正规随访患者术后3、6、12个月，HR-HPV的转阴率分别为57.27%、77.27%、89.09%，不同年龄段HR-HPV的转阴率分别为94.12%、93.75%、87.5%、66.67%，随着年龄的增长HR-HPV转阴率逐渐下降，而大于56岁的患者HR-HPV转阴率最低，与其他各年龄段比较，差异具有统计学意义(P<0.05)，各组正规随访患者TCT检查在随访期间均为阴性。结论：宫颈锥切术能够切除宫颈病变组织，但不能完全清除HR-HPV病毒，术后对各年龄段人群均需严密随诊。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the clinical outcome and follow-up results of patients with cervical intraepithelial neoplasia grade Ⅲ. Methods: 150 patients with cervical intraepithelial neoplasia grade III who were admitted for the first time in our hospital from June 2013 to June 2015 were followed up. Results: The rates of regular follow-up were 73.91%, 78.05%, 68.09%, 75% in different age groups. There was no statistical difference between different age groups(P>0.05). The negative rate was 57.27% after three months, 77.27% after six months, 89.09% after twelve months in regular follow up patients. The negative rates of HR-HPV were 94.12%, 93.75%, 87.5%, 66.67% in different age groups. And the HR-HPV negative rate of more than 56-year-old patients was the lowest, com- pared with other age groups(P<0.05). TCT was negative in different age groups. Conclusion: Cervical conization could remove diseased tissues, but couldn't clear the HPV virus. We should pay attention to follow the patients. |
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