| 刘诗煜,滕秀飞,白文娅,李秀艳,朱俊超.经皮穴位电刺激联合雷莫司琼对全麻术后恶心呕吐的影响[J].,2017,17(15):2953-2956 |
| 经皮穴位电刺激联合雷莫司琼对全麻术后恶心呕吐的影响 |
| Effect of Transcutaneous Electrical Acupoint Stimulation Combined with Ramosetron on Postoperative Nausea and Vomiting in Patients Under General Anesthesia |
| 投稿时间：2016-08-19 修订日期：2016-09-13 |
| DOI：10.13241/j.cnki.pmb.2017.15.040 |
| 中文关键词: 经皮穴位电刺激 胃泌素 术后恶心呕吐 |
| 英文关键词: Transcutaneous Electrical Acupoint Stimulation (TEAS) Gastrin Postoperative Nausea And Vomiting(PONV) |
| 基金项目:中国医科大学附属盛京医院三新项目（2015PS57J）；辽宁省自然科学基金项目（20102282） |
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| 中文摘要: |
| 摘要 目的：评价经皮穴位电刺激联合盐酸雷莫司琼对全麻术后恶心呕吐(PONV)的影响。方法：选择择期拟行全麻腹腔镜手术患者90例，随机分为三组。I组手术结束前15 min静脉给予盐酸雷莫司琼0.3 mg，II组麻醉诱导前30 min给予经皮电刺激30 min，III组重复上述两组操作。分别于入室(T0)、术毕(T1)、术后24 h(T2)采集外周静脉血样，测定胃泌素(GAS)浓度并记录术后24小时内PONV的发生情况。结果：与T0时比较，II组、III组T2时GAS浓度下降，I组T2时GAS浓度升高(P<0.05)；与I组比较，T2时II组、III组GAS浓度降低（P<0.05）；与I组、II组比较，III组术后PONV的发生率及发生的严重程度均下降(P<0.05)。I组、II组间PONV发生率及发生的严重程度无明显差异(P>0.05)。结论：经皮穴位电刺激可以降低全麻患者术后PONV的发生率，与盐酸雷莫司琼效果相近，二者联用止吐效果更佳，其机制可能与降低GAS浓度有关。 |
| 英文摘要: |
| ABSTRACT Objective: To evaluate the effect of transcutaneous electrical acupoint stimulation (TEAS) combined with ramosetron on postoperative nausea and vomiting (PONV) in patients underg general anesthesia. Methods: 90 patients under general anesthesia were randomly divided into three groups respectively. Group I was given 0.3 mg ramosetron intravenously 15 min before the end of the opera- tion, group II was treated with TEAS for 30 mins at 30 mins before anesthetic induction，and group III was treated with the combination treatment of group I and group II. The peripheral venous blood samples at the time point of upon entering the operating room(T0), at the end of the operation(T1), 24 h after the operation (T2) were collected to analyze the GAS concentration. The incidence rate of PONV within 24 h after the operation was recorded and compared between two groups. Results: Compared with the time point of T0, GAS con- centration decreased at T2 in group II and group III, and GAS concentration increased at T2 in group I(P<0.05); Compared with group I, GAS concentration decreased at T2 in group II and group III(P<0.05); compared with group I and group II, the incidence rate or the severity of PONV was decreased in group III. There was no statistical differences between group I and group II in the incidence rate or the severity of PONV (P>0.05). Conclusion: TEAS could reduce the incidence rate of PONV of patients undergo- ing general anesthesia and its effect was similar to ramosetron, the effect of combination of two treatments was better, and its mechanism might be related to the reduction of GAS concentration. |
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