| 吴 珊,高 艳,刘长存,赵凌舟,赵晋华.影像学方法在淋巴瘤疗效评估中的应用[J].,2017,17(14):2776-2779 |
| 影像学方法在淋巴瘤疗效评估中的应用 |
| Utility of Imaging Techniques in the Therapeutic Evaluation of Lymphoma |
| 投稿时间：2016-06-10 修订日期：2016-06-30 |
| DOI：10.13241/j.cnki.pmb.2017.14.044 |
| 中文关键词: 淋巴瘤 疗效评估 影像技术 |
| 英文关键词: Lymphoma Response evaluation Imaging techniques |
| 基金项目: |
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| 摘要点击次数: 368 |
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| 中文摘要: |
| 摘要：淋巴瘤通过放化疗可获得很高的治愈率。治疗过程中，疗效评估对于评价或调整治疗方案至关重要。基于病灶形态学改变的传统影像学技术如计算机断层扫描(computed tomography， CT)与磁共振成像(magnetic resonance imaging，MRI)技术在评估淋巴瘤疗效时存在一定的局限性；磁共振加权成像(diffusion-weighted imaging，DWI)结合水分子表观弥散系数(apparent diffusion coefficient，ADC)从分子水平反映疾病的病理生理状态，是一种功能成像新技术；而正电子发射断层显像/X 线计算机体层成像(Positron emission tomography/ computed tomography，PET/CT)将肿瘤的代谢与形态相结合，是一种新型的功能成像技术，已广泛应用于淋巴瘤患者的分期、疗效监测和预后评估中，可较其他影像学技术更准确的评估疗效；PET/MRI技术在淋巴瘤方面的临床应用研究目前尚处于初步阶段，其临床价值尚需进一步探讨。 |
| 英文摘要: |
| ABSTRACT: Patients suffering from lymphoma can be cured by radiotherapy and chemotherapy. During the treatment, it is crucial to evaluate the therapeutic effect for evaluating and adjusting the treatment plan. The conventional imaging techniques such as computed tomography (CT) and magnetic resonance imaging (MRI) have some limitations in evaluating the treatment response by monitoring the morphologic changes of the lesions. Diffusion- weighted imaging（DWI）with apparent diffusion coefficient (ADC) mapping is a new technique of functional magnetic resonance imaging. It evaluates the physiological and pathological state of disease on molecular level. F-18-labelled-fluorodeoxyglucose positron emission tomography/ computed tomography（ 18F-FDG PET/CT ）offers the advantage of combining functional and anatomical information, and it has been widely used in the lymphoma patients for staging, therapy monitoring and prognosis evaluation. It is better for PET/CT to evaluate the treatment response than other imaging techniques. PET/MRI has just begun to be used in the studies of lymphoma at present and its value should be further discussed. |
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