| 郝美嘉,陈文卫,王 氡,黄 慧,何 艳,刘 刚.冠心病患者颈动脉粥样硬化超声相关参数与病变严重程度的关系[J].,2017,17(12):2275-2278 |
| 冠心病患者颈动脉粥样硬化超声相关参数与病变严重程度的关系 |
| Relationship of Severity and Ultrasonic Parameters of Carotid Atherosclerosis in Patients with Coronary Heart Disease |
| 投稿时间：2016-12-26 修订日期：2017-01-16 |
| DOI：10.13241/j.cnki.pmb.2017.12.018 |
| 中文关键词: 冠心病 颈动脉粥样硬化 相关性 超声 |
| 英文关键词: Coronary heart disease Carotid atherosclerosis Correlation Ultrasonography |
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| 中文摘要: |
| 摘要 目的：研究冠心病患者颈动脉粥样硬化超声相关参数与病变严重程度的关系，为冠心病的诊断提供依据。方法：选取2015年1月至2016年6月我院收治的冠心病患者100例作为研究组，根据冠状动脉造影结果分为1支病变组（24例），2支病变组（44例）和3支病变组（32例）。根据Gensini评分分为轻度病变组（Gensini评分<20分，n=26），中度病变组（20分≤Gensini评分<40分，n=45）和重度病变组（Gensini评分≥40分，n=29）。另选取同期医院体检的健康体检者30例作为对照组。应用颈动脉超声多普勒检查各组颈动脉超声相关参数，采用Pearson相关性分析超声相关参数与病变严重程度的关系。结果：研究组颈动脉中膜厚度（IMT）、颈总动脉硬化度（β）、颈动脉顺应性（AC）、弹性系数（EP）、脉搏波传导速度（PEVβ）均显著高于对照组，差异有统计学意义（P＜0.05）。随着冠状动脉病变支数增加，受试者IMT、β、EP、AC、PEVβ升高，其中3支病变组>2支病变组>1支病变组>对照组（P＜0.05）。随着冠状动脉病变程度增加，受试者IMT、β、EP、AC、PEVβ升高，其中重度病变组>中度病变组>轻度病变组>对照组（P＜0.05）。经Pearson相关性分析显示：冠心病患者IMT、β、EP、AC、PEVβ与病变血管支数呈正相关（r=0.607，0.428，0.532，0.507，0.556，均P<0.05），与Gensini评分呈正相关（r=0.624，0.432，0.517，0.521，0.543，均P<0.05）。结论：冠心病患者颈动脉粥样硬化超声相关参数与患者病变程度相关，颈动脉超声检查可以作为冠心病的诊断手段。 |
| 英文摘要: |
| ABSTRACT Objective: To study the relationship of severity and ultrasonic parameters of carotid atherosclerosis in patients with coronary heart disease, and to provide evidence for the diagnosis of coronary heart disease. Methods: 100 patients with coronary heart disease who were treated in our hospital from January 2015 to June 2016 were selected as study group, which were divided into 1 vessel lesions group (24 cases), 2 vessel lesions group (44 cases) and 3 vessel lesions group (32 cases) according to the results of coronary angiography.And were divided into mild lesion group (Gensini score <20, n=26), moderate lesion group (20≤Gensini score <40, n=45) and severe lesion group (Gensini score ≥40, n=29) according to Gensini score. 30 cases of health examination in the hospital during the same period were selected as control group. Detect of carotid ultrasound parameters in each group according to carotid artery ultrasonography Doppler, and analyzed of the relationship of ultrasonic parameters and severity of lesions according to Pearson. Results: The carotid intima-media thickness (IMT), common carotid artery stiffness (β), carotid artery compliance (AC), elastic parameters (EP),pulse wave velocity (PEVβ) in the study group were significantly higher than those in the control group, the differences were statistically significant (P<0.05). The IMT, β, EP, AC and PEVβ were increased with the increased in numbers of coronary artery lesion, the 3 vessel lesions group>2 vessel lesions group>1 vessel lesions group>control group (P<0.05). The IMT, β, EP, AC and PEVβ were increased with the increased of severity of coronary artery disease,the severe lesion group>moderate lesion group>mild lesion group>control group (P<0.05). The IMT, β, EP, AC and PEVβ of patients with coronary heart disease and the number of diseased vessels were positively related (r=0.607, 0.428, 0.532, 0.507, 0.556, P <0.05), those and the Gensini score were positively related (r=0.624, 0.432, 0.517, 0.521, 0.543, P <0.05). Conclusion: The carotid ultrasound parameters and lesion severity in patients with coronary artery disease are relevant,carotid artery ultrasonography can be use as a diagnostic means for coronary heart disease. |
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