文章摘要
李松 江倩 彭丹 覃松柏 王永贞.冠心病患者胰岛素抵抗程度的影响因素分析[J].,2017,17(7):1294-1296
冠心病患者胰岛素抵抗程度的影响因素分析
Analysis of the Distribution Characteristics of Various Risk Factors inPatients with Coronary Heart Disease in Patients with Different Levels ofInsulin Resistance
  
DOI:
中文关键词: 冠心病  胰岛素抵抗  危险因素  分布特点
英文关键词: Coronary heart disease  Insulin resistance  Risk factors  Distribution characteristics
基金项目:湖北省自然科学基金项目(2003ABA183)
作者单位
李松 江倩 彭丹 覃松柏 王永贞 湖北中医药大学附属荆州市中医医院 
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中文摘要:
      目的:分析冠心病患者胰岛素抵抗程度的影响因素。方法:选择我院收治的冠心病住院患者166 例,根据胰岛素抵抗指数 (HOMA-IR)水平将其分成四组。A 组:HOMA-IR≤ 1.53(n=36);B 组:1.53<HOMA-IR≤ 3.46(n=30);C 组:3.46<HOMA-IR≤ 5.13 (n=36);D 组:HOMA-IR≥ 5.14(n=64)。检测和比较各组一般临床资料和相关生化指标的差异,并进一步分析影响冠心病患者胰岛 素抵抗程度的危险因素。结果:C、D组腰围、空腹血糖(FBG)、餐后2 h 血糖(2 hPBG)、低密度脂蛋白胆固醇(LDL-C)均高于A、B 组;D组空腹胰岛素(INS)均高于A、B 组,B、C 组INS、LDL-C 均高于A 组;D 组体质量、TC 高于A 组。上述差异均有统计学意义 (P<0.05)。多因素分析结果显示BMI、腰臀比(WHR)、FBG、INS、TC、HDL-C均是HOMA-IR 的影响因素(P<0.05)。结论:体重、腰 围、FBG、2hPBG、INS、TC、HDL-C 的上升均为加重冠心病患者胰岛素抵抗程度的危险因素。
英文摘要:
      Objective:To study the distribution characteristics of multiple risk factors in patients with coronary heart disease in patients with different levels of insulin resistance.Methods:166 cases of hospitalized patients with coronary heart disease in our hospital, according to insulin resistance index (HOMA-IR) level will be divided into four groups: group A: HOMA-IR was less than or equal to 1.53 (n=36); group B: 1.53 < HOMA-IR was less than or equal to 3.46 (n=30); group C 3.46 < HOMA-IR was less than or equal to 5.13 (n=36); group D: HOMA-IR was more than or equal to 5.14 (n=64). Used the stable model assessment insulin resistance level of coronary heart disease risk factors distribution.Results:C and D group's waist circumference, FBG, 2hPBG, LDL-C were higher than B, D group INS were higher than B, B group, INS, C group LDL-C, D group, A group, TC higher than A group. The difference was statistically significant (BMI, WHR, INS, TC, HDL-C, HOMA-IR) were statistically significant (P<0.05). Weight, waist circumference, 2hP- BG, TC, HDL-C, INS were increased in patients with coronary heart disease and insulin resistance in hospitalized patients with FBG.Conclusion:Body weight,waist circumference, FBG, 2hPBG, INS, TC, and HDL-C are all increased in patients with coronary heart disease and insulin resistance.
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