| 于冠宇,宋 超,冯 翔,周 建,景在平.血压波动性对主动脉夹层发生发展影响的研究进展[J].,2017,17(4):769-772 |
| 血压波动性对主动脉夹层发生发展影响的研究进展 |
| The Effect of Blood Pressure Variability on the Occurrence and Progression of Aortic Dissection |
| 投稿时间：2016-03-27 修订日期：2016-04-22 |
| DOI：10.13241/j.cnki.pmb.2017.04.044 |
| 中文关键词: 血压波动性 主动脉夹层 高血压 心血管疾病 |
| 英文关键词: Blood pressure variability Aortic dissection Hypertension Cardiovascular disease |
| 基金项目:国家自然科学基金项目（81330034；81270386；81273522） |
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| 中文摘要: |
| 摘要：高血压病是严重威胁人类健康的一类疾病。近年来研究表明，血压波动对于靶器官的损伤较高血压本身更大。主动脉夹层是一种与高血压密切相关的疾病。近年来，主动脉夹层的发生发展与血压波动的关系，越来越受到关注。血压波动性可造成内膜损伤和中膜层退行性变，从而在局部影响主动脉夹层的发生；还可通过免疫反应，炎性变化等全身因素造成主动脉夹层的发生。血压波动性在已发生主动脉夹层的患者中也是影响预后的重要因素。本文主要介绍血压波动性的分类和测量方法，以及对主动脉夹层发生发展影响的研究进展，旨在为临床医生进行主动脉夹层与血压波动性的关系研究提供参考。 |
| 英文摘要: |
| ABSTRACT: Hypertension is a kind of disease which seriously threatens human health. Recent studies have showed the target organ damage caused by blood pressure variability is greater than the high blood pressure. The relationship between hypertension and aortic dissection's occurrence and progression has attracted more and more attention recently. The variability of blood pressure can lead to local changes like the aortic vascular intima's damage and media's retrogression and induce systemic changes such as immune and inflammatory response, resulting in the occurrence of aortic dissection. Blood pressure variability is also an important factor affecting the prognosis of patients with aortic dissection already. The classification and measurement of the variability of blood pressure and the effect of blood pressure variability on the occurrence and progression of aortic dissection has been reviewed in this article with the purpose of providing a reference for the clinical study of the relationship between aortic dissection and blood pressure variability. |
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