| 苗艳 季景环 赵金梅 王春晓 邵迎华.硫酸镁联合小剂量阿司匹林对子痫先期患者氧化性低密度脂蛋白、
内脂素水平及临床疗效的影响[J].,2017,17(3):547-549 |
| 硫酸镁联合小剂量阿司匹林对子痫先期患者氧化性低密度脂蛋白、
内脂素水平及临床疗效的影响 |
| Effects of MagnesiumSulfate combined with Small Dose of Aspirin on theLevels of Oxidized Low Density Lipoprotein and Visfatin in Patients with Preeclampsia and Its Clinical Efficacy |
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| DOI： |
| 中文关键词: 硫酸镁 阿司匹林 子痫先期 氧化性低密度脂蛋白 内脂素 |
| 英文关键词: Magnesiumsulfate Aspirin Pre eclampsia Oxidized low density lipoprotein Visfatin |
| 基金项目:河北省自然科学基金项目(Z2012H091) |
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| 中文摘要: |
| 目的：探究硫酸镁联合小剂量阿司匹林对子痫前期患者氧化性低密度脂蛋白，内脂素水平及临床疗效的影响。方法：选取
2015 年1 月到2016年7 月我院收治的子痫先期患者90 例，根据随机数字对照表分为对照组与试验组，各45 例。对照组患者给
予静脉滴注硫酸镁治疗，试验组联合给予小剂量阿司匹林治疗。比较两组患者临床疗效、氧化性低密度脂蛋白及内脂素水平。结
果：治疗结束后，与对照组相比，试验组临床总有效率较高（P＜0.05），治疗后两组氧化性低密度脂蛋白及内脂素水平较治疗前降
低（P＜0.05）；与对照组相比，试验组氧化性低密度脂蛋白及内脂素水平较低（P＜0.05）。结论：硫酸镁联合小剂量阿司匹林对子痫
先期患者有明显治疗效果，推测其可能与氧化性低密度脂蛋白及内脂素水平降低有关。 |
| 英文摘要: |
| Objective:To investigate the effects of magnesium sulfate combined with small dose of aspirin on the levels of oxidized
low density lipoprotein and visfatin and its clinical efficacy for the patients with preeclampsia.Methods:90 patients with
preeclampsia who were treated in our hospital from January 2015 to July 2016 were selected and randomly divided into control group
and experiment group, with 45 cases in each group. The the patients in the control group were treated with the magnesium sulfate intravenous
drip, while the patients in the experiment group were treated with small dose of aspirin on the base of the control group. Then the
clinical efficacy, the levels of oxidized low density lipoprotein and visfatin levels of patients in the two groups were observed and compared
before and after the treatment.Results:After treatment, the clinical total effective rate of the experiment group was higher than that
of the control group (P<0.05); After treatment, the oxidized low-density lipoprotein and visfatin levels of the two groups were lower than
before treatment (P<0.05); Compared with control group, the oxidized low density lipoprotein and visfatin levels of the experiment group
were lower after the treatment (P<0.05).Conclusion:Magnesium sulfate combine with small dose of aspirin has obvious effect in the
treatment of pre eclampsia, which could be relative to the reduction of oxidized low density lipoprotein and visfatin levels. |
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