| 周芳 梁鹏 李洪林 宋文信 张少利.不稳定型心绞痛患者发病危险因素的性别差异分析[J].,2016,16(30):5952-5956 |
| 不稳定型心绞痛患者发病危险因素的性别差异分析 |
| The Gender Differences in Risk Factors of Patientswith Unstable Angina Pectoris |
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| DOI： |
| 中文关键词: 不稳定型心绞痛 性别 同型半胱氨酸 尿酸 叶酸 |
| 英文关键词: Unstable angina pectoris Gender Homocysteine Uric Acid Folic acid |
| 基金项目:河南省高等教育青年骨干教师计划资助项目(2009GGJS-085) |
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| 中文摘要: |
| 目的：探讨不同性别人群发生不稳定型心绞痛(UAP)的相关危险因素。方法：选择本院住院部收治的138 例UAP患者为
UAP组及80例同期经冠状动脉造影检查冠脉正常的非CHD者为对照组进行研究，对不同性别UAP患者发病的相关因素进行
分析和比较。结果：男性UAP 组和男性对照组在吸烟、高血压病史、高密度脂蛋白胆固醇(HDL-C)、半胱氨酸(Hcy)、维生素B12(Vit
B12)和叶酸(FA)方面存在显著性差异(P＜0.05)，两组其它指标比较无显著性差异(P＞0.05)；女性UAP 组和女性对照组在高血压病
史、糖尿病病史、尿酸(UA)、Hcy、VB12和FA 方面存在显著性差异(P＜0.05)，两组其它指标比较无显著性差异(P＞0.05)。Logistic
回归分析显示：吸烟、高血压、HDL、Hcy、和Vit B12水平为男性UAP 患者发病的独立危险因素(P＜0.05～0.01)；高血压、UA、Hcy、
Vit B12和FA 水平为女性UAP 患者发病的独立危险因素(P＜0.05)。结论：不同性别人群发生UAP 的危险因素不同，血浆Hcy和
UA水平为女性UAP的独立危险因素，而血浆Hcy 水平为男性UAP 的独立危险因素。 |
| 英文摘要: |
| Objective:To investigate the gender differences in risk factors of patients with unstable angina pectoris.Methods:138
cases of patients with UAP in our hospital were divided into UAP group. Another 80 cases of people who received coronary angiogram
inspection and were diagnosed without coronary heartdisease were used as control group. The general data were analyzed.Results:There
were significant difference in smoking, high density lipoprotein cholesterol(HDL), Homocysteine(Hcy), vitamin B12(Vit B12)and folic acid
(FA) between male UAP group and male control group (P<0.05). There were significant difference in high blood pressure. diabetes, Uric
acid (UA), Hcy, Vit B12 and FA between female UAP group and female control group (P<0.05 or P<0.01). Logistic regression analysis
showed that smoking, high blood pressure, HDL, Hcy and Vit B12 were independent risk factors of male UAP (P<0.05); high blood
pressur, UA, Hcy and Vit B12 were independent risk factors of female UAP (P<0.05).Conclusion:Different risk factors occur in different
gender groups of UAP. UA and Hcy are independent riskfactors of female UAP; Hcy is independent risk factor of male UAP, not for UA. |
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